Concepedia

Active Site Annotation

Active Site Annotation is a computational or experimental method that identifies and characterizes the specific region of a protein where catalytic activity occurs, differentiating it from other functional annotations by focusing exclusively on residues directly involved in substrate binding and chemical transformation.

10

Publications

1.3K

Citations

42

Authors

24

Institutions

Publications per year

2017–2026

2

Parents

Publications

10

The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data

C. T. Porter · Nucleic Acids Research · 2003 · 612 citations · Full text

, , +15

Predicting active site residue annotations in the Pfam database

Jaina Mistry, Alex Bateman, ROBERT FINN · BMC Bioinformatics · 2007 · 319 citations · Full text

, , +14

MOBscan: Automated Annotation of MOB Relaxases

M. Pilar Garcillán‐Barcia, Santiago Redondo, Luis Vielva et al. · Methods in molecular biology · 2019 · 137 citations

, , +8

Multi-modal deep learning enables efficient and accurate annotation of enzymatic active sites

Xiaorui Wang, Xiaodan Yin, Dejun Jiang et al. · Nature Communications · 2024 · 37 citations · Full text

, , +12

Enhanced performance in prediction of protein active sites with THEMATICS and support vector machines

Wenxu Tong, Ronald J. Williams, Ying Wei et al. · Protein Science · 2007 · 36 citations · Full text

, , +15

1–5 of 10

Authors

42

  1. MM
    Mona Motwani

    University of Massachusetts Chan Medical School, United States

    1 publications · 14 citations

    1

    h-index

  2. FD
    Fernando de la Cruz

    Universidad de Cantabria, Spain

    1 publications · 137 citations

    1

    h-index

  3. RF
    ROBERT FINN

    European Bioinformatics Institute, United Kingdom

    1 publications · 319 citations

    1

    h-index

  4. YW
    Ying Wei

    Northeastern University, United States

    1 publications · 36 citations

    1

    h-index

  5. KK
    Konstantinos Karagiannis

    Center for Biologics Evaluation and Research, United States

    1 publications · 14 citations

    1

    h-index

1–5 of 42

Institutions

24

  1. Zhejiang University

    Hangzhou, China

    1 h-index

    9 publications

    333 citations

  2. Indiana University of Pennsylvania

    Indiana, United States

    1 h-index

    1 publications

    36 citations

  3. George Washington University

    Washington, United States

    1 h-index

    4 publications

    56 citations

  4. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    1 h-index

    1 publications

    37 citations

  5. National Institutes of Health

    Bethesda, United States

    1 h-index

    4 publications

    120 citations

  6. United States Food and Drug Administration

    Silver Spring, United States

    1 h-index

    1 publications

    14 citations

  7. National Center for Biotechnology Information

    Bethesda, United States

    1 h-index

    4 publications

    120 citations

  8. Instituto de Biomedicina y Biotecnología de Cantabria

    Santander, Spain

    1 h-index

    3 publications

    411 citations

1–8 of 24

Venues

  1. BMC Bioinformatics

    2 publications · 341 citations

    2

    h-index

  2. Nature Communications

    1 publications · 37 citations

    1

    h-index

  3. Current Protocols in Bioinformatics

    1 publications · 13 citations

    1

    h-index

  4. Methods in molecular biology

    Book series · 1 publications · 137 citations

    1

    h-index

  5. FEBS Journal

    1 publications · 14 citations

    1

    h-index

1–5