Concepedia

Actionable Genomic Alterations

Actionable Genomic Alterations is a genomic alteration that meets defined criteria for clinical relevance, distinguished by its capacity to guide targeted therapeutic interventions, inform prognosis, or influence clinical decision-making in cancer precision medicine based on empirical or predictive evidence.

409

Publications

34.4K

Citations

5.5K

Authors

1.1K

Institutions

Publications per year

2017–2026

328

Parents

Publications

409

Oncogenic Signaling Pathways in The Cancer Genome Atlas

Francisco Sánchez-Vega, Marco Mina, Joshua Armenia et al. · Cell · 2018 · 3.4K citations · Full text

, , +17

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata et al. · Cancer Discovery · 2015 · 1.1K citations · Full text

, , +17

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

Leticia De Mattos‐Arruda, Regina Mayor, Charlotte K.Y. Ng et al. · Nature Communications · 2015 · 858 citations · Full text

, , +17

A framework to rank genomic alterations as targets for cancer precision medicine: the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT)

Joaquı́n Mateo, Debyani Chakravarty, Rodrigo Dienstmann et al. · Annals of Oncology · 2018 · 787 citations · Full text

, , +17

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

Jordi Barretina, Barry S. Taylor, Shantanu Banerji et al. · Nature Genetics · 2010 · 726 citations · Full text

, , +14

1–5 of 409

Authors

5.5K

  1. JS
    Jeffrey S. Ross

    Foundation Medicine (United States)

    24 publications · 3.5K citations

    22

    h-index

  2. RK
    Razelle Kurzrock

    The University of Texas MD Anderson Cancer Center, United States

    18 publications · 1.3K citations

    18

    h-index

  3. VA
    Vincent A. Miller

    Foundation Medicine (United States)

    17 publications · 2.8K citations

    17

    h-index

  4. SM
    Siraj M. Ali

    Foundation Medicine (United States)

    18 publications · 2.6K citations

    17

    h-index

  5. MF
    Michael F. Berger

    Memorial Sloan Kettering Cancer Center, United States

    13 publications · 3.6K citations

    14

    h-index

1–5 of 5.5K

Institutions

1.1K

  1. Memorial Sloan Kettering Cancer Center

    New York, United States

    32 h-index

    541 publications

    203.5K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    30 h-index

    285 publications

    41.6K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    26 h-index

    183 publications

    90.6K citations

  4. Foundation Medicine (United States)

    Cambridge, United States

    24 h-index

    263 publications

    36.7K citations

  5. Harvard University

    Cambridge, United States

    23 h-index

    121 publications

    34.3K citations

  6. Guardant (United States)

    Redwood City, United States

    15 h-index

    58 publications

    7.6K citations

  7. Heidelberg University

    Heidelberg, Germany

    15 h-index

    220 publications

    21.9K citations

  8. University of Michigan

    Ann Arbor, United States

    14 h-index

    101 publications

    19.8K citations

1–8 of 1.1K

Venues

  1. Clinical Cancer Research

    28 publications · 4.5K citations

    24

    h-index

  2. JCO Precision Oncology

    24 publications · 1.4K citations

    19

    h-index

  3. Cancers

    20 publications · 542 citations

    17

    h-index

  4. Journal of Clinical Oncology

    24 publications · 1.8K citations

    16

    h-index

  5. Cancer Discovery

    13 publications · 3.5K citations

    13

    h-index

1–5