Concepedia

Actin Severing

Actin Severing is a cytoskeletal regulatory process in which actin filaments are selectively cleaved into shorter fragments by specialized proteins, thereby modulating filament dynamics and cellular architecture.

306

Publications

22.6K

Citations

1.1K

Authors

352

Institutions

Publications per year

2017–2026

42

Parents

Publications

306

Mechanism of Actin Filament Turnover by Severing and Nucleation at Different Concentrations of ADF/Cofilin

Ernesto Andrianantoandro, Thomas D. Pollard · Molecular Cell · 2006 · 692 citations · Full text

, , +13

Structure of gelsolin segment 1-actin complex and the mechanism of filament severing

Paul McLaughlin, John Gooch, Hans Georg Mannherz et al. · Nature · 1993 · 573 citations

, , +14

F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex

Michael P. Murrell, Margaret L. Gardel · Proceedings of the National Academy of Sciences · 2012 · 434 citations · Full text

, , +17

Actin-depolymerizing Factor and Cofilin-1 Play Overlapping Roles in Promoting Rapid F-Actin Depolymerization in Mammalian Nonmuscle Cells

Pirta Hotulainen, Eija Paunola, Maria K. Vartiainen et al. · Molecular Biology of the Cell · 2004 · 381 citations · Full text

, , +17

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

Kimihide Hayakawa, Hitoshi Tatsumi, Masahiro Sokabe · The Journal of Cell Biology · 2011 · 348 citations · Full text

, , +17

1–5 of 306

Authors

1.1K

  1. LB
    Laurent Blanchoin

    Centre National de la Recherche Scientifique, France

    11 publications · 1.5K citations

    11

    h-index

  2. AG
    Alan G. Weeds

    MRC Laboratory of Molecular Biology, United Kingdom

    11 publications · 1.4K citations

    11

    h-index

  3. RR
    Robert Robinson

    Institute of Molecular and Cell Biology, Singapore

    10 publications · 897 citations

    10

    h-index

  4. EM
    Enrique M. De La Cruz

    Yale University, United States

    10 publications · 1.1K citations

    10

    h-index

  5. TD
    Thomas D. Pollard

    Yale University, United States

    9 publications · 1.6K citations

    9

    h-index

1–5 of 1.1K

Institutions

352

  1. Yale University

    New Haven, United States

    21 h-index

    67 publications

    6.7K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    19 h-index

    72 publications

    5.1K citations

  3. Harvard University

    Cambridge, United States

    12 h-index

    43 publications

    1.6K citations

  4. Université Joseph Fourier

    Grenoble, France

    12 h-index

    26 publications

    3.4K citations

  5. University of California, Los Angeles

    Los Angeles, United States

    9 h-index

    28 publications

    1.6K citations

  6. Max Planck Institute of Biochemistry

    Martinsried, Germany

    9 h-index

    31 publications

    2.5K citations

  7. Brigham and Women's Hospital

    Boston, United States

    9 h-index

    37 publications

    2.3K citations

  8. Laboratoire Physiologie Cellulaire & Végétale

    Grenoble, France

    9 h-index

    11 publications

    1.1K citations

1–8 of 352

Venues

  1. Journal of Biological Chemistry

    JBC · 54 publications · 4K citations

    37

    h-index

  2. The Journal of Cell Biology

    JCB · 26 publications · 3.2K citations

    24

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 16 publications · 1.6K citations

    16

    h-index

  4. Journal of Cell Science

    16 publications · 1.3K citations

    15

    h-index

  5. Biochemistry

    13 publications · 541 citations

    13

    h-index

1–5