Concepedia

Actin Depolymerizers

Actin Depolymerizers is a class of pharmacological agents that induce the disassembly of filamentous actin cytoskeleton by accelerating the dissociation of actin monomers from microfilaments, thereby disrupting cytoskeletal integrity and dynamics.

439

Publications

31.7K

Citations

1.9K

Authors

574

Institutions

Publications per year

2017–2026

43

Parents

Publications

439

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

Midori Maekawa, Toshimasa Ishizaki, Shuken Boku et al. · Science · 1999 · 1.6K citations

, , +17

Actin Depolymerizing Factor (ADF/Cofilin) Enhances the Rate of Filament Turnover: Implication in Actin-based Motility

Marie-France Carlier, Valérie Laurent, Jérôme Santolini et al. · The Journal of Cell Biology · 1997 · 1.1K citations · Full text

, , +17

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

Hiroaki Miki, Takuya Sasaki, Yoshimi Takai et al. · Nature · 1998 · 648 citations

, , +13

Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change

James F. Casella, Michael D. Flanagan, Shin Lin · Nature · 1981 · 495 citations

, , +17

Actin microfilaments play a critical role in endocytosis at the apical but not the basolateral surface of polarized epithelial cells.

T A Gottlieb, Ivan E. Ivanov, Milton Adesnik et al. · The Journal of Cell Biology · 1993 · 437 citations · Full text

, , +16

1–5 of 439

Authors

1.9K

  1. JR
    James R. Bamburg

    Colorado State University, United States

    13 publications · 1.8K citations

    13

    h-index

  2. HK
    Hideo Kigoshi

    University of Tsukuba, Japan

    14 publications · 520 citations

    12

    h-index

  3. AG
    Alan G. Weeds

    MRC Laboratory of Molecular Biology, United Kingdom

    10 publications · 1.1K citations

    10

    h-index

  4. SO
    Shoichiro Ono

    Emory University, United States

    9 publications · 488 citations

    9

    h-index

  5. IM
    Issei Mabuchi

    The University of Tokyo, Japan

    8 publications · 460 citations

    8

    h-index

1–5 of 1.9K

Institutions

574

  1. The University of Tokyo

    Tokyo, Japan

    13 h-index

    46 publications

    3.8K citations

  2. University of Pennsylvania

    Philadelphia, United States

    13 h-index

    36 publications

    2.9K citations

  3. Inserm

    Paris, France

    12 h-index

    63 publications

    3.7K citations

  4. University of Tsukuba

    Tsukuba, Japan

    12 h-index

    68 publications

    1.9K citations

  5. Harvard University

    Cambridge, United States

    11 h-index

    51 publications

    3.3K citations

  6. Colorado State University

    Fort Collins, United States

    11 h-index

    36 publications

    4.7K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    40 publications

    4.2K citations

  8. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    10 h-index

    19 publications

    2.1K citations

1–8 of 574

Venues

  1. Journal of Biological Chemistry

    JBC · 42 publications · 4.3K citations

    34

    h-index

  2. The Journal of Cell Biology

    JCB · 28 publications · 4.4K citations

    26

    h-index

  3. Biochemistry

    13 publications · 1.2K citations

    13

    h-index

  4. PubMed

    Repository · 11 publications · 299 citations

    11

    h-index

  5. FEBS Letters

    11 publications · 784 citations

    11

    h-index

1–5