Concepedia

Acetaminophen-alcohol Interactions

Acetaminophen-Alcohol Interactions is a pharmacological phenomenon characterized by the metabolic and hepatotoxic consequences arising from the concurrent use of acetaminophen and alcohol, primarily mediated through the induction of cytochrome P450 2E1 and the depletion of glutathione in the liver.

18

Publications

623

Citations

51

Authors

26

Institutions

Publications per year

2017–2026

0

Parents

Publications

18

Apparent Potentiation of Acetaminophen Hepatotoxicity by Alcohol

Harvey Licht · Annals of Internal Medicine · 1980 · 89 citations

, , +16

Impact of Liver Disease, Alcohol Abuse, and Unintentional Ingestions on the Outcomes of Acetaminophen Overdose

A SHAHEEN, S. Dean, Hude Quan · Clinical Gastroenterology and Hepatology · 2008 · 84 citations

, , +17

Ethanol induction of acetaminophen toxicity and metabolism

Francis J. Peterson, David E. Holloway, Richard R. Erickson et al. · Life Sciences · 1980 · 66 citations

, , +10

Concomitant alcohol and drug abuse enhancing acetaminophen toxicity. Report of a case.

R Goldfinger, Khaqan Ahmed, C. S. Pitchumoni et al. · PubMed · 1978 · 56 citations

, , +14

Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility

Renato D. Lópes, John D. Horowitz, David García et al. · Blood · 2011 · 40 citations · Full text

, , +14

1–5 of 18

Authors

51

  1. PH
    Peter H. Duquette

    University of Minnesota, United States

    1 publications · 66 citations

    1

    h-index

  2. SD
    S. Dean

    KU Leuven, Belgium

    1 publications · 84 citations

    1

    h-index

  3. KF
    Kieran F. Scott

    UNSW Sydney, Australia

    1 publications · 29 citations

    1

    h-index

  4. EA
    Edward A. Carter

    Massachusetts General Hospital, United States

    1 publications · 12 citations

    1

    h-index

  5. CS
    C. S. Pitchumoni

    Lady of Mercy Medical Center, United States

    1 publications · 56 citations

    1

    h-index

1–5 of 51

Institutions

26

  1. Harvard University

    Cambridge, United States

    2 h-index

    4 publications

    126 citations

  2. University of New Mexico

    Albuquerque, United States

    1 h-index

    1 publications

    40 citations

  3. Duke Medical Center

    Durham, United States

    1 h-index

    1 publications

    40 citations

  4. Cambridge Hospital

    Cambridge, United States

    1 h-index

    3 publications

    114 citations

  5. Boston University

    Boston, United States

    1 h-index

    1 publications

    40 citations

  6. Washington University Medical Center

    St Louis, United States

    1 h-index

    3 publications

    267 citations

  7. Alberta Health Services

    Edmonton, Canada

    1 h-index

    1 publications

    84 citations

  8. West Virginia University

    Morgantown, United States

    1 h-index

    3 publications

    42 citations

1–8 of 26

Venues

  1. PubMed

    Repository · 4 publications · 108 citations

    4

    h-index

  2. Archives of Internal Medicine

    2 publications · 41 citations

    2

    h-index

  3. Life Sciences

    1 publications · 66 citations

    1

    h-index

  4. Alcohol

    1 publications · 12 citations

    1

    h-index

  5. Biochemical Pharmacology

    1 publications · 36 citations

    1

    h-index

1–5