Concepedia

Abscopal Effect

The "Abscopal Effect" is a rare systemic anti-tumor phenomenon in which localized radiotherapy induces regression of metastatic cancer lesions at distant, non-irradiated sites, mediated by activation of the immune system.

447

Publications

37.2K

Citations

4.8K

Authors

1.1K

Institutions

Publications per year

2017–2026

330

Variants

Abscopal Phenomenon

Parents

Publications

447

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

Michael A. Postow, Margaret K. Callahan, Christopher A. Barker et al. · New England Journal of Medicine · 2012 · 2.1K citations · Full text

, , +17

DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity

Claire Vanpouille‐Box, Amandine Alard, Molykutty J. Aryankalayil et al. · Nature Communications · 2017 · 1.7K citations · Full text

, , +17

Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

Md. Zahidunnabi Dewan, Ashley E. Galloway, Noriko Kawashima et al. · Clinical Cancer Research · 2009 · 1.6K citations · Full text

, , +17

Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

Sandra Demaria, Bruce Ng, M. Devitt et al. · International Journal of Radiation Oncology*Biology*Physics · 2004 · 1.4K citations

, , +16

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

Chunbai He, Xiaopin Duan, Nining Guo et al. · Nature Communications · 2016 · 755 citations · Full text

, , +17

1–5 of 447

Authors

4.8K

  1. SC
    Silvia C. Formenti

    New York University, United States

    16 publications · 7.6K citations

    15

    h-index

  2. SD
    Sandra Demaria

    Cornell University, United States

    14 publications · 7.2K citations

    13

    h-index

  3. MA
    María Angélica Cortez

    The University of Texas MD Anderson Cancer Center, United States

    8 publications · 764 citations

    8

    h-index

  4. JW
    James W. Welsh

    The University of Texas MD Anderson Cancer Center, United States

    8 publications · 764 citations

    8

    h-index

  5. HB
    Hampartsoum B. Barsoumian

    The University of Texas MD Anderson Cancer Center, United States

    8 publications · 764 citations

    8

    h-index

1–5 of 4.8K

Institutions

1.1K

  1. Cornell University

    Ithaca, United States

    22 h-index

    90 publications

    36.7K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    16 h-index

    245 publications

    19.3K citations

  3. Memorial Sloan Kettering Cancer Center

    New York, United States

    14 h-index

    167 publications

    22.5K citations

  4. Heidelberg University

    Heidelberg, Germany

    12 h-index

    25 publications

    1.2K citations

  5. Shandong First Medical University

    Jinan, China

    11 h-index

    44 publications

    2.1K citations

  6. Brigham and Women's Hospital

    Boston, United States

    11 h-index

    40 publications

    2.4K citations

  7. Dana-Farber Cancer Institute

    Boston, United States

    11 h-index

    58 publications

    2.7K citations

  8. Chinese Academy of Sciences

    Beijing, China

    10 h-index

    45 publications

    4.6K citations

1–8 of 1.1K

Venues

  1. Journal for ImmunoTherapy of Cancer

    JITC · 23 publications · 1.6K citations

    21

    h-index

  2. 17

    h-index

  3. Frontiers in Oncology

    14 publications · 408 citations

    12

    h-index

  4. OncoImmunology

    14 publications · 1.2K citations

    12

    h-index

  5. Journal of Clinical Oncology

    14 publications · 744 citations

    12

    h-index

1–5