PPM1A Regulates Antiviral Signaling by Antagonizing TBK1-Mediated STING Phosphorylation and Aggregation

Zexing Li, Ge Liu, Liwei Sun, +7

PLoS Pathogens

Sting AggregationSystems BiologySignal TransductionMolecular PhysiologySignaling Pathway +13

A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures

Xiao Liang, Jun Xiao, Xuzichao Li, +14

Nature Chemical Biology

BiochemistryG Protein-coupled ReceptorNatural SciencesMolecular BiologyCarbohydrate-protein Interaction +2

The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination

Chang Liu, Shan Huang, Xuelin Wang, +8

The Journal of Immunology

ImmunologyMolecular BiologyInnate ImmunityCellular PhysiologySignaling Pathway +17

Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD

Wei Lin, Jing Zhang, Haiyan Lin, +9

Nature Communications

DDAH2 suppresses RLR-MAVS–mediated innate antiviral immunity by stimulating nitric oxide–activated, Drp1-induced mitochondrial fission

Shan Huang, Zexing Li, Zewen Wu, +5

Science Signaling

Competition between PAF1 and MLL1/COMPASS confers the opposing function of LEDGF/p75 in HIV latency and proviral reactivation

Ru Gao, Jiaqian Bao, Han Yan, +14

Science Advances

<i>ASXL1</i> mutations accelerate bone marrow fibrosis via EGR1-TNFA axis-mediated neoplastic fibrocyte generation in myeloproliferative neoplasms

Zhongxun Shi, Jinqin Liu, Yingying Zhao, +17

Haematologica

Mixed-phenotype Acute LeukemiaImmunologyMyeloproliferative NeoplasmsPathologyTumor Biology +16

Construction and validation of prognostic signature for hepatocellular carcinoma basing on hepatitis B virus related specific genes

Lei Wang, Manman Qiu, Lili Wu, +4

Infectious Agents and Cancer

PRRSV degrades MDA5 via dual autophagy receptors P62 and CCT2 to evade antiviral innate immunity

Ruiqi Sun, Yanyu Guo, Lilin Zhang, +8

Virologica Sinica

Recombinant hemagglutinin protein and DNA-RNA-combined nucleic acid vaccines harbored by yeast elicit protective immunity against H9N2 avian influenza infection

Huixia Zhang, Ruyu Xie, Han Zhang, +7

Poultry Science