RNA m6A methyltransferase METTL3 regulates invasiveness of melanoma cells by matrix metallopeptidase 2

Ujwal Dahal, Kang Le, Mamta Gupta

Melanoma Research

ImmunologyMolecular BiologyCancer BiologyMelanoma CellsTumor Biology +16

Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates β-amyloid deposition through upregulating α-secretase in vivo and in vitro

Zhengrong Mei, Fangyan Zhang, Liang Tao, +8

Neuroscience Letters

Protein SecretionBiochemistryProtein Misfoldingβ-Amyloid DepositionPharmacology +2

Inhibition of the CEBPβ-NFκB interaction by nanocarrier-packaged Carnosic acid ameliorates glia-mediated neuroinflammation and improves cognitive function in an Alzheimer’s disease model

Yi-Bin Wang, Xiang Li, Yang Bing, +10

Cell Death and Disease

Fenofibrate ameliorates cardiac hypertrophy by activation of peroxisome proliferator-activated receptor-α partly via preventing p65-NFκB binding to NFATc4

Jian Zou, Kang Le, Suowen Xu, +8

Molecular and Cellular Endocrinology

Molecular PharmacologyCardiac MuscleCardiomyopathyMolecular PhysiologyCardiovascular Disease +11

Icaritin, a novel plant-derived osteoinductive agent, enhances the osteogenic differentiation of human bone marrow- and human adipose tissue-derived mesenchymal stem cells

Tao Wu, Tao Shu, Kang Le, +5

International Journal of Molecular Medicine

Tissue EngineeringHuman Bone Marrow-Bone Regenerative MedicineMatrix MineralizationOsteoporosis +19

Laparoscopic Uterine Artery Occlusion Combined with Myomectomy for Uterine Myomas

Zhongping Cheng, Weihong Yang, Hong Dai, +3

Journal of Minimally Invasive Gynecology

LaparoscopyGynecologic SurgeryUterine FibroidsGynecological SurgeryUterine Myomas +3

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex

Kang Le, Chun-Chun Li, Guan Ye, +2

Proceedings of the National Academy of Sciences

PPARα activation inhibits endothelin-1-induced cardiomyocyte hypertrophy by prevention of NFATc4 binding to GATA-4

Kang Le, Ruifang Li, Suowen Xu, +10

Archives of Biochemistry and Biophysics

CardiomyopathyMolecular PhysiologySignal TransductionEndothelin-1-induced Cardiomyocyte HypertrophyMedicine +8

Mantle cell lymphoma polarizes tumor-associated macrophages into M2-like macrophages, which in turn promote tumorigenesis

Kang Le, Jing Ping Sun, Hunain Khawaja, +4

Blood Advances

Tumor-associated MacrophagesImmunologyImmunoeditingPathologyMcl Tumor +14

Identification of Differently Expressed mRNAs in Atherosclerosis Reveals CDK6 Is Regulated by circHIPK3/miR-637 Axis and Promotes Cell Growth in Human Vascular Smooth Muscle Cells

Kang Le, Jia Hao, Ben Huang, +6

Frontiers in Genetics

Vascular DiseaseImmunologyMolecular BiologyPromotes Cell GrowthCellular Physiology +22