Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial

Zixian Wang, Chengxu Cui, Jun Yao, +78

Cancer Cell

Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial

Shukui Qin, Minshan Chen, Ann‐Lii Cheng, +202

The Lancet

Surgical OncologyHepatologyMedicinePathologyHigh-risk Hepatocellular Carcinoma +6

Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single‐arm phase II study

Zhi Peng, Tianshu Liu, Jia Wei, +32

Cancer Communications

Effective PEGylation of Iron Oxide Nanoparticles for High Performance In Vivo Cancer Imaging

Dongfang Liu, Wei Wu, Jingjing Ling, +3

Advanced Functional Materials

NanoparticlesNanotherapeuticsEngineeringIron Oxide NanoparticlesDense Peg Coating +17

miRNA-148a serves as a prognostic factor and suppresses migration and invasion through Wnt1 in non-small cell lung cancer

Yong Chen, Lingfeng Min, Chuanli Ren, +7

PLoS ONE

OncologyPrognostic FactorMedicinePathologySuppresses Migration +13

miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling

Yong Chen, Ying Sun, Longbang Chen, +5

Molecular Medicine Reports

E-cadherin-mediated Pten/aktBreast OncologyMedicineBreast Cancer CellsImmunology +9

Systematic Assessment of the Toxicity and Potential Mechanism of Graphene Derivatives <i>In Vitro</i> and <i>In Vivo</i>

Jian Li, Xizhi Zhang, Jing Jiang, +5

Toxicological Sciences

NanotherapeuticsEngineeringBio-based NanomaterialsChemistryOxidative Stress +14

First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial

Lin Shen, Yanqiao Zhang, Ziyu Li, +84

Nature Medicine

Esophageal CancerGastrointestinal OncologyMedicineFirst-line CadonilimabGastroenterology +6

Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer (CT041-ST-01): a randomised, open-label, phase 2 trial

Chang Liu, Zhi Peng, Yanqiao Zhang, +29

The Lancet

Gastro-oesophageal Junction CancerEsophageal CancerGastrointestinal OncologyMedicineGastroenterology +8

Bubble Microreactors Triggered by an Alternating Magnetic Field as Diagnostic and Therapeutic Delivery Devices

Fang Yang, Ping Chen, Wen He, +6

Small

NanoparticlesEngineeringMagnetic ResonanceBiomedical EngineeringFerrofluid +15