A ketogenic diet suppresses seizures in mice through adenosine A1 receptors

Susan A. Masino, Tianfu Li, Panos Theofilas, +6

Journal of Clinical Investigation

Adenosine DeficiencyAdenosine A1 ReceptorsNeurophysiologyMedicineAdenosine Kinase +10

Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice

Tianfu Li, Gaoying Ren, Theresa A. Lusardi, +6

Journal of Clinical Investigation

Adenosine KinaseCellular NeurobiologySynaptic SignalingCellular PhysiologySocial Sciences +16

Adenosine A1 receptors are crucial in keeping an epileptic focus localized

Denise Fedele, Tianfu Li, Jing Lan, +2

Experimental Neurology

Adenosine A1 ReceptorsSignal TransductionEpileptic FocusNeurophysiologyMedicine +9

Silk polymer-based adenosine release: Therapeutic potential for epilepsy

Andrew Wilz, Eleanor M. Pritchard, Tianfu Li, +3

Biomaterials

Therapeutic PotentialSmart PolymerMedicineNeuropharmacologyBiomedical Engineering +2

A novel mouse model for sudden unexpected death in epilepsy (SUDEP): Role of impaired adenosine clearance

Hai‐Ying Shen, Tianfu Li, Detlev Boison

Epilepsia

Adenosine ReceptorsAdenosine KinasePharmacotherapyExperimental PharmacologySocial Sciences +15

Adenosine dysfunction in astrogliosis: cause for seizure generation?

Tianfu Li, Jing Lan, Bertil B. Fredholm, +2

Neuron Glia Biology

Neuro-oncologyAdenosine A1 ReceptorsMolecular NeuroscienceNeurophysiologyMedicine +12

Antiepileptic effects of silk-polymer based adenosine release in kindled rats

Cory Szybala, Eleanor M. Pritchard, Theresa A. Lusardi, +4

Experimental Neurology

PharmacologyAdenosine ReleaseMedicineNeuropharmacology

Lentiviral RNAi-induced downregulation of adenosine kinase in human mesenchymal stem cell grafts: A novel perspective for seizure control

Gaoying Ren, Tianfu Li, Jiang Quan Lan, +3

Experimental Neurology

Regenerative MedicineInduced Pluripotent Stem CellCell TherapyTransplantationMedicine +11

Human mesenchymal stem cell grafts engineered to release adenosine reduce chronic seizures in a mouse model of CA3-selective epileptogenesis

Tianfu Li, Gaoying Ren, David L. Kaplan, +1

Epilepsy Research

Regenerative MedicineCa3-selective EpileptogenesisInduced Pluripotent Stem CellDevelopmental BiologyCell Therapy +11

Heating phenomenon in unclean composite insulators

Cong Wang, Tianfu Li, Youping Tu, +4

Engineering Failure Analysis

Materials ScienceThermal InsulationUnclean Composite InsulatorsEngineeringApplied Physics +6