Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis

Shu Zhang, Wen Fang, Siqi Zhou, +18

Nature Communications

Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma

Fa Yang, Wei Yan, Donghui Han, +16

Cancer Research

ImmunologyPathologyCancer BiologyTumor BiologyInflammation +18

Single-cell analysis of multiple cancer types reveals differences in endothelial cells between tumors and normal tissues

Jiayu Zhang, Tong Lü, Shiqi Lu, +10

Computational and Structural Biotechnology Journal

Endothelial CellsTip-like EcsPathologyTumor EcsCancer Biology +16

Expression of Prostate-Specific Membrane Antigen in Tumor-Associated Vasculature Predicts Poor Prognosis in Hepatocellular Carcinoma

Dian Jiao, Yu Li, Fa Yang, +12

Clinical and Translational Gastroenterology

High mobility group box 1 promotes the epithelial-to-mesenchymal transition in prostate cancer PC3 cells via the RAGE/NF-κB signaling pathway

Jingliang Zhang, Shuai Shao, Donghui Han, +9

International Journal of Oncology

ImmunologyCancer BiologyTumor BiologySignaling PathwayCell Regulation +15

Establishment and prospective validation of an SUV_max cutoff value to discriminate clinically significant prostate cancer from benign prostate diseases in patients with suspected prostate cancer by ⁶⁸Ga-PSMA PET/CT: a real-world study

Jianhua Jiao, Fei Kang, Jingliang Zhang, +12

Theranostics

A reference single-cell regulomic and transcriptomic map of cynomolgus monkeys

Jiao Qu, Fa Yang, Tao Zhu, +11

Nature Communications

Therapeutic effects of human monoclonal PSMA antibody-mediated TRIM24 siRNA delivery in PSMA-positive castration-resistant prostate cancer

Shengjia Shi, Lijuan Wang, Donghui Han, +12

Theranostics

Single-cell analysis reveals the COL11A1+ fibroblasts are cancer-specific fibroblasts that promote tumor progression

Jiayu Zhang, Shiqi Lu, Tong Lü, +11

Frontiers in Pharmacology

Comparison of 68Ga-PSMA-617 PET/CT with mpMRI for the detection of PCa in patients with a PSA level of 4–20 ng/ml before the initial biopsy

Yu Li, Donghui Han, Peng Wu, +14

Scientific Reports