Targeted Disruption of <i>Smad4</i> in Cardiomyocytes Results in Cardiac Hypertrophy and Heart Failure

Jian Wang, Ning Xu, Xinheng Feng, +6

Circulation Research

Smad4 is required for the normal organization of the cartilage growth plate

Jishuai Zhang, Xiaohong Tan, Wenlong Li, +4

Developmental Biology

MechanobiologyMusculoskeletal ResearchDevelopmental BiologyNormal OrganizationBone Morphogenic Protein +7

Targeted Disruption of Smad4 in Mouse Epidermis Results in Failure of Hair Follicle Cycling and Formation of Skin Tumors

Leilei Yang, Chunming Mao, Yan Teng, +8

Cancer Research

Smad4 is required for maintaining normal murine postnatal bone homeostasis

Xiaohong Tan, Tujun Weng, Jishuai Zhang, +13

Journal of Cell Science

SclerostinDevelopmental BiologyBone Morphogenic ProteinOsteoarthritisBone Metabolism +8

Smad4 Deficiency in Smooth Muscle Cells Initiates the Formation of Aortic Aneurysm

Peng Zhang, Siyuan Hou, Jicheng Chen, +11

Circulation Research

A novel CD19/CD22/CD3 trispecific antibody enhances therapeutic efficacy and overcomes immune escape against B-ALL

Lijun Zhao, Shuhong Li, Xiaoyi Wei, +8

Blood

T-LAK Cell-originated Protein Kinase (TOPK) Phosphorylation of Prx1 at Ser-32 Prevents UVB-induced Apoptosis in RPMI7951 Melanoma Cells through the Regulation of Prx1 Peroxidase Activity

Tatyana A. Zykova, Feng Zhu, T. I. Vakorina, +5

Journal of Biological Chemistry

ApoptosisCell DeathDermatologyTumor BiologyOxidative Stress +14

MST1 Promotes Apoptosis through Phosphorylation of Histone H2AX

Weihong Wen, Feng Zhu, Jishuai Zhang, +9

Journal of Biological Chemistry

ApoptosisImmunologyCell DeathHistone H2axEpigenetics +14

Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation

Xiaohong Tan, Tong Lu, Lin Li, +20

Nature Communications

Cyclin-Dependent Kinase 3–Mediated Activating Transcription Factor 1 Phosphorylation Enhances Cell Transformation

Duo Zheng, Yong‐Yeon Cho, Andy T. Y. Lau, +4

Cancer Research

Cell CycleGliomaTumor BiologyNeuro-oncologyTranscriptional Regulation +16