PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation

Min Xie, Yan Yu, Rui Kang, +10

Nature Communications

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis

Liangchun Yang, Min Xie, Minghua Yang, +9

Nature Communications

InflammationCytokineMolecular PhysiologyDisease PathophysiologyPathogenesis +10

The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

Yu Yan, Yangchun Xie, Lizhi Cao, +6

Molecular & Cellular Oncology

Chemotherapeutic AgentsTumor BiologyPotent Ferroptosis InhibitorHematological MalignancyMedicine +11

HMGB1 regulates erastin-induced ferroptosis via RAS-JNK/p38 signaling in HL-60/NRAS^Q61L cells.

Fanghua Ye, Wenwen Chai, Min Xie, +4

PubMed

Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis

Minghua Yang, Lizhi Cao, Min Xie, +5

Biochemical Pharmacology

InflammationCytokineAnti-inflammatoryLethal SepsisMedicine +11

HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells

Wenwen Chai, Fanghua Ye, Li Zeng, +2

Journal of Experimental & Clinical Cancer Research

Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis

Liangchun Yang, Fanghua Ye, Jiao Liu, +3

Autophagy

InflammationAcute PancreatitisCell AutophagyAnti-inflammatoryInflammatory Disease +13

microRNA<i>30A</i>promotes autophagy in response to cancer therapy

Yan Yu, Lizhi Cao, Liangchun Yang, +3

Autophagy

Cancer TherapyCell AutophagyMir30a MimicsAutophagyAutophagy Serves +11

S100A8 Contributes to Drug Resistance by Promoting Autophagy in Leukemia Cells

Minghua Yang, Zeng Pei, Rui Kang, +4

PLoS ONE

MitophagyImmunologyLeukemia CellsCancer BiologyTumor Biology +14

Up-regulated autophagy by endogenous high mobility group box-1 promotes chemoresistance in leukemia cells

Liangchun Yang, Yu Yan, Rui Kang, +8

Leukemia & lymphoma/Leukemia and lymphoma

MitophagyImmunologyCell DeathLeukemia CellsRapamycin Complex 1 +16