Shinichiro Niimi

Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks

Kazuaki Matsuoka, Makoto Iimori, Shinichiro Niimi et al. · Molecular Cancer Therapeutics · 2015 · 61 citations

Medicine, Oncology, Pharmacology +14

Cdc6 Protein Obstructs Apoptosome Assembly and Consequent Cell Death by Forming Stable Complexes with Activated Apaf-1 Molecules

Shinichiro Niimi, Shiho Arakawa-Takeuchi, Baasanjav Uranbileg et al. · Journal of Biological Chemistry · 2012 · 43 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis

Shinichi Kiyonari, Makoto Iimori, Kazuaki Matsuoka et al. · Molecular Cancer Therapeutics · 2015 · 34 citations · Full text

Medicine, Pharmacology, Carcinogenesis +12

The antibodies against 5-bromo-2′-deoxyuridine specifically recognize trifluridine incorporated into DNA

Hiroyuki Kitao, Yosuke Morodomi, Shinichiro Niimi et al. · Scientific Reports · 2016 · 27 citations · Full text

Medicine, Molecular Biology, Oncology +13

Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level

Yuki Kataoka, Makoto Iimori, Shinichiro Niimi et al. · Scientific Reports · 2019 · 21 citations · Full text

Medicine, Molecular Biology, Oncology +11