Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis

Shirit Einav, Doron Gerber, Paul D. Bryson, +5

Nature Biotechnology

Microfluidic Affinity AnalysisPharmaceutical ResearchEngineeringDrug TargetViral Hepatitis +10

Amphipathic Helix-Dependent Localization of NS5A Mediates Hepatitis C Virus RNA Replication

Menashe Elazar, Kwang Ho Cheong, Ping Liu, +3

Journal of Virology

Virus StructureViral ReplicationBiochemistryHepatitis C VirusMembrane Localization +12

An N-Terminal Amphipathic Helix in Hepatitis C Virus (HCV) NS4B Mediates Membrane Association, Correct Localization of Replication Complex Proteins, and HCV RNA Replication

Menashe Elazar, Ping Liu, Charles M. Rice, +1

Journal of Virology

A Nucleotide Binding Motif in Hepatitis C Virus (HCV) NS4B Mediates HCV RNA Replication

Shirit Einav, Menashe Elazar, Tsafi Danieli, +1

Journal of Virology

A novel quantitative microarray antibody capture assay identifies an extremely high hepatitis delta virus prevalence among hepatitis B virus–infected mongolians

Xiaohua Chen, Odgerel Oidovsambuu, Ping Liu, +13

Hepatology

The Anti-Hepatitis C Agent Nitazoxanide Induces Phosphorylation of Eukaryotic Initiation Factor 2α Via Protein Kinase Activated by Double-Stranded RNA Activation

Menashe Elazar, Michael Liu, Sean A. McKenna, +5

Gastroenterology

Transcriptional RegulationSignal TransductionSignaling PathwayViral HepatitisDouble-stranded Rna Activation +6

The hepatitis C virus NS5A inhibitor (BMS-790052) alters the subcellular localization of the NS5A non-structural viral protein

Choongho Lee, Han Ma, Julie Q. Hang, +5

Virology

Virus StructureViral ReplicationMolecular VirologyHepatologyViral Hepatitis +8

A Rab-GAP TBC Domain Protein Binds Hepatitis C Virus NS5A and Mediates Viral Replication

Ella H. Sklan, Kirk A. Staschke, Tina M. Oakes, +5

Journal of Virology

Potential for Hepatitis C Virus Resistance to Nitazoxanide or Tizoxanide

Brent E. Korba, Menashe Elazar, Ping Lui, +2

Antimicrobial Agents and Chemotherapy

Identification of a Class of HCV Inhibitors Directed Against the Nonstructural Protein NS4B

Nam‐Joon Cho, Hadas Dvory‐Sobol, Choongho Lee, +5

Science Translational Medicine