BET Bromodomain Proteins Mediate Downstream Signaling Events following Growth Factor Stimulation in Human Lung Fibroblasts and Are Involved in Bleomycin-Induced Pulmonary Fibrosis

Xiaoyan Tang, Ruoqi Peng, Yonglin Ren, +12

Molecular Pharmacology

3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models

Michael Soth, Johannes C. Hermann, Calvin Yee, +36

Journal of Medicinal Chemistry

Drug TargetJanus KinasesImmunologyCellular PharmacologyPharmacotherapy +19

Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells

Daina Z. Ewton, Jing Hu, Maria Vilenchik, +7

Molecular Cancer Therapeutics

Radiation OncologyPancreatic CancerChemoprevention StrategyOncogenic AgentMedicine +13

High‐Throughput Confocal Microscopy for β‐Arrestin–Green Fluorescent Protein Translocation G Protein‐Coupled Receptor Assays Using the Evotec Opera

Ralph Garippa, Ann F. Hoffman, Gabriele Gradl, +1

Methods in enzymology on CD-ROM/Methods in enzymology

Immunocytochemical TechniqueSignal TransductionG Protein-coupled ReceptorHigh‐throughput Confocal MicroscopyReceptor (Biochemistry) +7

A Pharmaceutical Company User's Perspective on the Potential of High Content Screening in Drug Discovery

Ann F. Hoffman, Ralph Garippa

Humana Press eBooks

Pharmaceutical ResearchEngineeringHit IdentificationDrug ScreeningBiomedical Engineering +18

Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates

Alexandra Hicks, Robert A. Goodnow, Gary Cavallo, +41

Prostaglandins & Other Lipid Mediators

AsthmaInflammationPulmonary Arterial HypertensionInflammatory Lung DiseasePulmonary Inflammation +13

Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization

Jaspreet Banga, Dinesh Srinivasan, Chia-Chi Sun, +24

Science Advances

Molecular cloning and regulation of expression of the genes for initiation factor 3 and two aminoacyl-tRNA synthetases

Dirk Elseviers, Patricia J. Gallagher, Ann F. Hoffman, +2

Journal of Bacteriology

GeneticsMolecular BiologyMolecular GeneticsGene TranscriptionProtein Synthesis +16

Purification and Characterization of a Phospholipase A2 from Human Osteoarthritic Synovial Fluid

Thomas P. Parks, Susan Lukas, Ann F. Hoffman

Advances in experimental medicine and biology

InflammationRheumatologyBiochemistryOsteoarthritisProtein Phosphorylation +6

Discovery of Novel and Potent Leukotriene B₄Receptor Antagonists. Part 1

Robert A. Goodnow, Alexandra Hicks, Achyutharao Sidduri, +39

Journal of Medicinal Chemistry