MERTK receptor tyrosine kinase is a therapeutic target in melanoma

Jennifer Schlegel, Maria J. Sambade, Susan Sather, +22

Journal of Clinical Investigation

Mertk ExpressionSkin CancerMedicineReceptor Tyrosine KinaseMelanoma +9

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia

Alisa B. Lee‐Sherick, K M Eisenman, Susan Sather, +12

Oncogene

UNC569, a Novel Small-Molecule Mer Inhibitor with Efficacy against Acute Lymphoblastic Leukemia <i>In Vitro</i> and <i>In Vivo</i>

Sandra Christoph, Deborah DeRyckere, Jennifer Schlegel, +18

Molecular Cancer Therapeutics

Chemoprevention StrategyKinase InhibitorsMolecular BiologyTumor BiologyHematological Malignancy +16

Solution Characterization of the Extracellular Region of CD147 and Its Interaction with Its Enzyme Ligand Cyclophilin A

Jennifer Schlegel, Jasmina S. Redzic, Christopher C. Porter, +9

Journal of Molecular Biology

Solution CharacterizationExtracellular RegionProtein FunctionGranulocyteImmunology +3

Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia

Luis Brandão, Amanda Winges, Sandra Christoph, +8

Blood Cancer Journal

Hematological MalignancyTumor BiologyMedian SurvivalMedicineMixed-phenotype Acute Leukemia +11

Characterizing and controlling the inherent dynamics of cyclophilin‐A

Jennifer Schlegel, Geoffrey S. Armstrong, Jasmina S. Redzic, +2

Protein Science

Protein ChemistryProtein AssemblyBiochemistryProtein FoldingNatural Sciences +13

Prolonged Exposure to a Mer Ligand in Leukemia: Gas6 Favors Expression of a Partial Mer Glycoform and Reveals a Novel Role for Mer in the Nucleus

Justine Migdall-Wilson, C Ryan Bates, Jennifer Schlegel, +4

PLoS ONE

Mixed-phenotype Acute LeukemiaMolecular BiologyTumor BiologyHematological MalignancyCell Regulation +17

Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission

Sandra Christoph, Jennifer Schlegel, Francesca Alvarez‐Calderon, +4

Journal of Hematology & Oncology

Endotoxin-tolerant mice produce an inhibitor of tumor necrosis factor synthesis

F. Ulrich Schade, Jennifer Schlegel, Kathryn J. Hofmann, +2

Journal of Endotoxin Research

Tnf SynthesisImmunotoxicologyImmunologyImmune RegulationCell Death +14

Formation of a TNF synthesis inhibitor in endotoxin tolerance.

Schade Fu, C Franke, Jennifer Schlegel, +1

PubMed

InflammationMolecular PharmacologyEndotoxin ToleranceImmunotoxicologyImmunology +4