Upregulation of Periostin and Reactive Stroma Is Associated with Primary Chemoresistance and Predicts Clinical Outcomes in Epithelial Ovarian Cancer

Lisa Ryner, Yinghui Guan, Ron Firestein, +11

Clinical Cancer Research

A multicenter, single‐arm, open‐label, phase 2 study of apitolisib (GDC‐0980) for the treatment of recurrent or persistent endometrial carcinoma (MAGGIE study)

Vicky Makker, Fernando O. Recio, Ling Ma, +13

Cancer

Low-pass Whole-genome Sequencing of Circulating Cell-free DNA Demonstrates Dynamic Changes in Genomic Copy Number in a Squamous Lung Cancer Clinical Cohort

Xiaoji Chen, Ching‐Wei Chang, Jill M. Spoerke, +11

Clinical Cancer Research

Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer

Jiping Zha, Carol O’Brien, Heidi Savage, +9

Molecular Cancer Therapeutics

Breast OncologyHuman GrowthIgf-ir ExpressionImmunologyEstrogen Receptor +17

Anti-atherosclerotic effect of simvastatin depends on the presence of apolipoprotein E

Yi-Xin Wang, Baby Martin-McNulty, Ling‐Yuh Huw, +7

Atherosclerosis

InflammationThrombosisVascular DiseaseApolipoprotein ECardiovascular Disease +10

Mosunetuzumab with polatuzumab vedotin in relapsed or refractory aggressive large B cell lymphoma: a phase 1b/2 trial

Lihua E. Budde, Adam J. Olszewski, Sarit Assouline, +21

Nature Medicine

Loss of CD20 expression as a mechanism of resistance to mosunetuzumab in relapsed/refractory B-cell lymphomas

Stephen J. Schuster, Ling‐Yuh Huw, Christopher R. Bolen, +14

Blood

Systems‐based digital twins to help characterize clinical <scp>dose–response</scp> and propose predictive biomarkers in a Phase I study of bispecific antibody, mosunetuzumab, in <scp>NHL</scp>

Monica Susilo, Chi‐Chung Li, Kapil Gadkar, +7

Clinical and Translational Science

EngineeringImmunodeficienciesImmunologyIndolent NhlT-cell Infiltration +24

Tctex2: A Sperm Tail Surface Protein Mapping to the t-Complex

Ling‐Yuh Huw, Andrew S. Goldsborough, Keith R. Willison, +1

Developmental Biology

Germ CellMedicineNatural SciencesGameteMolecular Biology +5

Combination of Atezolizumab and Tazemetostat in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Results From a Phase Ib Study

Maria Lia Palomba, Guillaume Cartron, Leslie Popplewell, +10

Clinical Lymphoma Myeloma & Leukemia