Human Immunodeficiency Virus Type 1 Escapes from RNA Interference-Mediated Inhibition

Atze T. Das, Thijn R. Brummelkamp, Ellen M. Westerhout, +4

Journal of Virology

Rna Interference-mediated InhibitionViral ReplicationNeurovirologyRna InterferenceMedicine +13

Optimization of the Tet-On system for regulated gene expression through viral evolution

Xue Zhou, Monique Vink, Bep Klaver, +2

Gene Therapy

Viral ReplicationSystems BiologyEngineeringViral EvolutionTet-on System +10

Viral Evolution as a Tool to Improve the Tetracycline-regulated Gene Expression System

Atze T. Das, Xue Zhou, Monique Vink, +4

Journal of Biological Chemistry

<i>In vitro</i> evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies

Giuseppe Marzio, Koen Verhoef, Monique Vink, +1

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyImmunodominanceAntiviral DrugImmunotherapy +16

Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategies

Ying Poi Liu, Monique Vink, Jan-Tinus Westerink, +4

RNA

Viral ReplicationEngineeringGeneticsImmunologyDifferent Mechanisms +19

Selecting the optimal Tet‐On system for doxycycline‐inducible gene expression in transiently transfected and stably transduced mammalian cells

Atze T. Das, Xue Zhou, Stefan Metz, +2

Biotechnology Journal

EngineeringAdaptive Immune SystemT-regulatory CellImmunologyImmunotherapy +15

Efficient Human Immunodeficiency Virus Replication Requires a Fine-Tuned Level of Transcription

Giuseppe Marzio, Monique Vink, Koen Verhoef, +2

Journal of Virology

A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication

Ellen M. Westerhout, Monique Vink, P. C. Joost Haasnoot, +2

Molecular Therapy

Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control

Xue Zhou, Monique Vink, Ben Berkhout, +1

Retrovirology

Construction of a Doxycycline-Dependent Simian Immunodeficiency Virus Reveals a Nontranscriptional Function of Tat in Viral Replication

Atze T. Das, Bep Klaver, Alex Harwig, +4

Journal of Virology

Viral ReplicationNontranscriptional FunctionImmunologyMolecular BiologyImmunotherapy +14