The evolutionarily conserved MAPK/Erk signaling promotes ancestral T-cell immunity in fish via c-Myc–mediated glycolysis

Xiumei Wei, Yu Zhang, Li Cheng, +4

Journal of Biological Chemistry

Ancestral T Cells in Fish Require mTORC1-Coupled Immune Signals and Metabolic Programming for Proper Activation and Function

Xiumei Wei, Kete Ai, Huiying Li, +3

The Journal of Immunology

Fish NF‐κB couples TCR and IL‐17 signals to regulate ancestral T‐cell immune response against bacterial infection

Xiumei Wei, Li Cheng, Yu Zhang, +6

The FASEB Journal

Ca2+–Calcineurin Axis–Controlled NFAT Nuclear Translocation Is Crucial for Optimal T Cell Immunity in an Early Vertebrate

Xiumei Wei, Huiying Li, Yu Zhang, +4

The Journal of Immunology

IL-2–mTORC1 signaling coordinates the STAT1/T-bet axis to ensure Th1 cell differentiation and anti-bacterial immune response in fish

Kete Ai, Kang Li, Xinying Jiao, +5

PLoS Pathogens

IL-10 Negatively Controls the Primary T Cell Response of Tilapia by Triggering the JAK1/STAT3/SOCS3 Axis That Suppresses NF-κB and MAPK/ERK Signaling

Kang Li, Jiaqi Li, Xiumei Wei, +8

The Journal of Immunology

Tilapia Produce Il-10Adaptive Immune SystemInnate Immune SystemImmunologyImmune Regulation +28

Expression pattern analysis of IRF4 and its related genes revealed the functional differentiation of IRF4 paralogues in teleost

Kete Ai, Kai Luo, Youshen Li, +6

Fish & Shellfish Immunology

Signal TransductionDevelopmental BiologyGeneticsExpression Pattern AnalysisRelated Genes +10

TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3- and Foxp3-mediated transcriptional networks

Qian Zhang, Ming Geng, Kang Li, +5

Journal of Biological Chemistry

Role of scavenger receptor from Octopus ocellatus as a co-receptor of Toll-like receptor in initiation of TLR-NF-κB signaling during anti-bacterial response

Xiumei Wei, Tianyu Zhao, Kete Ai, +5

Developmental & Comparative Immunology

InflammationToll-like ReceptorsHost ResponseMicrobial PathogensPathogenesis +13

Cloning and expression of Asian swamp eel (Monopterus albus) cxcr4 paralogues, and their modulation by pathogen infection

Weihua Gao, Liu Fang, Daiqin Yang, +7

Aquaculture

BiologyCxcr4 ParaloguesPathogen InfectionPathogenesisAsian Swamp Eel +3