Assessment of Blood Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Patients With Non–Small Cell Lung Cancer With Use of a Next-Generation Sequencing Cancer Gene Panel

Zhijie Wang, Jianchun Duan, Shangli Cai, +27

JAMA Oncology

Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma

Zijian Yang, Cong Yan, Jiaqiang Ma, +12

Nature Metabolism

Lactylome AnalysisLiverHepatologyBiochemistryMetabolic Reprogramming +12

Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma

Liangqing Dong, Dayun Lu, Ran Chen, +29

Cancer Cell

Tumor BiologyHepatologyProteogenomic Characterization IdentifiesHepatobiliary TumorBiliary Cancer +5

Comutations in DNA Damage Response Pathways Serve as Potential Biomarkers for Immune Checkpoint Blockade

Zhijie Wang, Jing Zhao, Guoqiang Wang, +18

Cancer Research

Identification of Deleterious <i>NOTCH</i> Mutation as Novel Predictor to Efficacious Immunotherapy in NSCLC

Kai Zhang, Xiaohua Hong, Zhengbo Song, +19

Clinical Cancer Research

Risk factors for pneumonitis in patients treated with anti‐programmed death‐1 therapy: A case‐control study

Pengfei Cui, Zhefeng Liu, Guoqiang Wang, +12

Cancer Medicine

A Novel Online Calculator Based on Serum Biomarkers to Detect Hepatocellular Carcinoma among Patients with Hepatitis B

Tian Yang, Hao Xing, Guoqiang Wang, +17

Clinical Chemistry

Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology

Shuyi Ji, Feng Li, Zile Fu, +31

Science Translational Medicine

Tumor BiologyMedicineLiver PhysiologyHepatobiliary TumorPharmacology +10

Allele Frequency–Adjusted Blood-Based Tumor Mutational Burden as a Predictor of Overall Survival for Patients With NSCLC Treated With PD-(L)1 Inhibitors

Zhijie Wang, Jianchun Duan, Guoqiang Wang, +30

Journal of Thoracic Oncology

Overall SurvivalMedicinePathologyImmune Checkpoint InhibitorNsclc Treated +4

TP53 Mutation as Potential Negative Predictor for Response of Anti-CTLA-4 Therapy in Metastatic Melanoma

Wenjing Xiao, Nan Du, Taoyuan Huang, +10

EBioMedicine