Cavity as a Source of Conformational Fluctuation and High-Energy State: High-Pressure NMR Study of a Cavity-Enlarged Mutant of T4Lysozyme

Akihiro Maeno, Dan Sindhikara, Fumio Hirata, +6

Biophysical Journal

BiochemistryCavity-enlarged MutantNatural SciencesMagnetic ResonanceMolecular Biology +8

Locomotive syndrome is associated with body composition and cardiometabolic disorders in elderly Japanese women

Misa Nakamura, Yosuke Kobashi, Hiroshi Hashizume, +6

BMC Geriatrics

<i>V</i><i>_i</i> -Value Analysis:  A Pressure-Based Method for Mapping the Folding Transition State Ensemble of Proteins

Lally Mitra, Kazumi Hata, Ryohei Kono, +7

Journal of the American Chemical Society

Molecular BiologyAnalytical UltracentrifugationProtein RefoldingTransition StatePressure Dependence +17

Structural plasticity of staphylococcal nuclease probed by perturbation with pressure and pH

Ryo Kitahara, Kazumi Hata, Akihiro Maeno, +11

Proteins Structure Function and Bioinformatics

Protein AssemblyMolecular BiologyInternal GroupsStructural PlasticityProtein Folding +14

A Delicate Interplay of Structure, Dynamics, and Thermodynamics for Function: A High Pressure NMR Study of Outer Surface Protein A

Ryo Kitahara, Alana K. Simorellis, Kazumi Hata, +4

Biophysical Journal

Protein ChemistryBiomolecular Structure PredictionProtein FoldingMolecular BiologyDelicate Interplay +7

The pressure-temperature phase diagram of hen lysozyme at low pH

Akihiro Maeno, Hiroshi Matsuo, Kazuyuki Akasaka

BIOPHYSICS

Teriparatide Improves Bone and Lipid Metabolism in a Male Rat Model of Type 2 Diabetes Mellitus

Sachiko Nomura, Akihiro Kitami, Ryoko Takao-Kawabata, +9

Endocrinology

Endogenous calcitonin regulates lipid and glucose metabolism in diet-induced obesity mice

Misa Nakamura, Sachiko Nomura, Tadashi Yamakawa, +7

Scientific Reports

Pressure-Accelerated Dissociation of Amyloid Fibrils in Wild-Type Hen Lysozyme

Buddha Ram Shah, Akihiro Maeno, Hiroshi Matsuo, +2

Biophysical Journal

Protein FoldingAmyloid FibrilsExperimental BiophysicsRheologyProtein Misfolding +2

Pressure acceleration of proteolysis: A general mechanism

Kazuyuki Akasaka, Harumi Nagahata, Akihiro Maeno, +1

BIOPHYSICS

High Hydrostatic PressureRemarkable AccelerationProtein AssemblyMolecular BiologyKbar Range +16