Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation

Hongwei Qin, Wen-I Yeh, Patrizia De Sarno, +10

Proceedings of the National Academy of Sciences

Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226

Christopher A. Fuhrman, Wen-I Yeh, Howard R. Seay, +15

The Journal of Immunology

Receptors TigitDistinct Treg SubsetsT-regulatory CellImmunologyImmune Regulation +16

Avidity and Bystander Suppressive Capacity of Human Regulatory T Cells Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes

Wen-I Yeh, Howard R. Seay, Brittney N. Newby, +6

Frontiers in Immunology

IFNγ inhibits Th17 differentiation and function via Tbet-dependent and Tbet-independent mechanisms

Wen-I Yeh, Ian L. McWilliams, Laurie E. Harrington

Journal of Neuroimmunology

Transcriptional RegulationSignal TransductionImmunologyImmunologic MechanismInnate Immunity +7

Innate inflammation drives NK cell activation to impair Treg activity

Joseph Dean, Leeana D. Peters, Christopher A. Fuhrman, +12

Journal of Autoimmunity

InflammationNatural Killer CellsAllergyAutoimmune DiseaseTreg Activity +12

CD226 Deletion Reduces Type 1 Diabetes in the NOD Mouse by Impairing Thymocyte Development and Peripheral T Cell Activation

Melanie R. Shapiro, Wen-I Yeh, Joshua R. Longfield, +11

Frontiers in Immunology

Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism

Wei Li, Minghao Gong, Yuk Pheel Park, +10

JCI Insight

Mitochondrial DysfunctionGeneticsT-regulatory CellImmunologyImmune Regulation +19

Autoreactive Tbet-Positive CD4 T Cells Develop Independent of Classic Th1 Cytokine Signaling during Experimental Autoimmune Encephalomyelitis

Wen-I Yeh, Ian L. McWilliams, Laurie E. Harrington

The Journal of Immunology

Treg-Specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T-Cell Stability

Puchong Thirawatananond, Matthew E. Brown, Lindsey K. Sachs, +6

Diabetes

A chimeric antigen receptor uniquely recognizing MICA/B stress proteins provides an effective approach to target solid tumors

John Goulding, Wen-I Yeh, Bryan Hancock, +24

Med