SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism

Tianshi Wang, Ying Cao, Quan Zheng, +23

Molecular Cell

Mitochondrial FunctionMitochondrial DynamicMitochondrial BiologyMetabolic SignalingMedicine +3

Arginine Methylation of MDH1 by CARM1 Inhibits Glutamine Metabolism and Suppresses Pancreatic Cancer

Yiping Wang, Wei Zhou, Jian Wang, +9

Molecular Cell

Tumor BiologyPancreatic CancerBiochemistryMedicinePharmacology +6

SUMO-Specific Protease 2 Is Essential for Suppression of Polycomb Group Protein-Mediated Gene Silencing during Embryonic Development

Xunlei Kang, Yitao Qi, Yong Zuo, +5

Molecular Cell

Developmental BiologyProtein ExpressionDevelopmental GeneticsGeneticsMolecular Genetics +7

Glucose limitation activates AMPK coupled SENP1-Sirt3 signalling in mitochondria for T cell memory development

Jianli He, Xun Shangguan, Wei Zhou, +25

Nature Communications

Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with Apaf-1

Yong Zuo, Binggang Xiang, Jie Yang, +4

Cell Research

InflammationCaspase-9 FacilitatesReductive StressSignal TransductionBiochemistry +11

SENP1-Sirt3 signaling promotes α-ketoglutarate production during M2 macrophage polarization

Wei Zhou, Gaolei Hu, Jianli He, +14

Cell Reports

InflammationSignal TransductionM2 PolarizationSignaling PathwayMacrophage Activation +12

Platelet P2Y12 Is Involved in Murine Pulmonary Metastasis

Yanhua Wang, Yueping Sun, Ding Li, +5

PLoS ONE

Platelet Aggregation InhibitorsPlatelet P2y12Tumor MicroenvironmentBlood PlateletMedicine +11

SUMO-specific protease 1 regulates the in vitro and in vivo growth of colon cancer cells with the upregulated expression of CDK inhibitors

Ying Xu, Jie Li, Yong Zuo, +3

Cancer Letters

Tumor BiologyCdk InhibitorsSignaling PathwayMedicineColon Cancer Cells +9

Induction of SENP1 in Endothelial Cells Contributes to Hypoxia-driven VEGF Expression and Angiogenesis

Ying Xu, Yong Zuo, Haizeng Zhang, +7

Journal of Biological Chemistry

Endothelial CellsHypoxia-driven Vegf ExpressionImmunologyRenal InflammationCellular Physiology +19

Differential expression of SUMO-specific protease 7 variants regulates epithelial–mesenchymal transition

Tasneem Bawa‐Khalfe, Long‐Sheng Lu, Yong Zuo, +4

Proceedings of the National Academy of Sciences

Molecular RegulationSumo-specific Protease 7Cancer BiologyTumor BiologyTranscriptional Regulation +16