Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis

Xucheng Hou, Xinfu Zhang, Weiyu Zhao, +7

Nature Nanotechnology

Cell-based Drug DeliveryNanomedicineEngineeringImmunologySepsis +6

Long-term storage of lipid-like nanoparticles for mRNA delivery

Pengxuan Zhao, Xucheng Hou, Jinyue Yan, +5

Bioactive Materials

Intratumoral delivery of IL-12 and IL-27 mRNA using lipid nanoparticles for cancer immunotherapy

Jin-Qing Liu, Chengxiang Zhang, Xinfu Zhang, +12

Journal of Controlled Release

Cell-based Drug DeliveryNanomedicineTumor ImmunologyIntratumoral DeliveryImmunology +8

Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing

Xinfu Zhang, Weiyu Zhao, Giang N. Nguyen, +17

Science Advances

Leveraging mRNA Sequences and Nanoparticles to Deliver SARS‐CoV‐2 Antigens In Vivo

Chunxi Zeng, Xucheng Hou, Jinyue Yan, +5

Advanced Materials

VaccinationNasar Mrnas MeritVaccine DevelopmentVaccine TargetImmunology +12

Biomimetic nanoparticles deliver mRNAs encoding costimulatory receptors and enhance T cell mediated cancer immunotherapy

Wenqing Li, Xinfu Zhang, Chengxiang Zhang, +12

Nature Communications

Close the cancer–immunity cycle by integrating lipid nanoparticle–mRNA formulations and dendritic cell therapy

Yuebao Zhang, Xucheng Hou, Shi Du, +8

Nature Nanotechnology

NanomedicineMedicineCancer–immunity CycleImmunologyTumor Immunity +10

Adoptive cell therapy for cancer treatment

Shi Du, Jinyue Yan, Yonger Xue, +2

Exploration

Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system

Chang Wang, Yonger Xue, Tamara Markovic, +26

Nature Materials

NanoparticlesNanomedicineBlood–brain-barrier-crossing Lipid NanoparticlesEngineeringBlood–brain Barrier +8

STING Agonist-Derived LNP-mRNA Vaccine Enhances Protective Immunity Against SARS-CoV-2

Yuebao Zhang, Jinyue Yan, Xucheng Hou, +9

Nano Letters

EngineeringImmunologyInnate ImmunityImmunotherapySynthetic Immunology +14