Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions

Sumiyo Morita, Hirofumi Noguchi, Takuro Horii, +8

Nature Biotechnology

Natural SciencesMolecular BiologyDna ReplicationGene EditingDna Demethylation +4

The SOCS Box of SOCS-1 Accelerates Ubiquitin-dependent Proteolysis of TEL-JAK2

Shintaro Kamizono, Toshikatsu Hanada, Hideo Yasukawa, +11

Journal of Biological Chemistry

Validation of microinjection methods for generating knockout mice by CRISPR/Cas-mediated genome engineering

Takuro Horii, Yuji Arai, Miho Yamazaki, +5

Scientific Reports

miR-29 Represses the Activities of DNA Methyltransferases and DNA Demethylases

Sumiyo Morita, Takuro Horii, Mika Kimura, +3

International Journal of Molecular Sciences

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationMolecular Biology +16

One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation

Sumiyo Morita, Takuro Horii, Mika Kimura, +3

Genomics

ChromatinNatural SciencesGeneticsDna MethylationEpigenetic Change +9

MeCP2-dependent repression of an imprinted miR-184 released by depolarization

Tasuku Nomura, Mika Kimura, Takuro Horii, +4

Human Molecular Genetics

Autism Spectrum DisordersEpigenetic ChangeGeneticsDna MethylationEpigenetics +17

Microarray analysis of promoter methylation in lung cancers

Masayuki Fukasawa, Mika Kimura, Sumiyo Morita, +9

Journal of Human Genetics

Epigenetic ChangeGeneticsCancer GenomicsMicroarray AnalysisGene Expression +3

Generation of an ICF Syndrome Model by Efficient Genome Editing of Human Induced Pluripotent Stem Cells Using the CRISPR System

Takuro Horii, Daiki Tamura, Sumiyo Morita, +2

International Journal of Molecular Sciences

EngineeringGeneticsCrispr SystemGenome EngineeringCrispr +15

Stat5a regulates T helper cell differentiation by several distinct mechanisms

Shin‐ichiro Kagami, Hiroshi Nakajima, Akira Suto, +7

Blood

Mammalian Twisted Gastrulation Is Essential for Skeleto-Lymphogenesis

Tetsuya Nosaka, Sumiyo Morita, Hidetomo Kitamura, +13

Molecular and Cellular Biology

Lymphocyte DevelopmentImmunologyEmbryologyTissue DevelopmentMammalian Twisted Gastrulation +15