Single-crystal x-ray diffraction structures of covalent organic frameworks

Tianqiong Ma, Eugene A. Kapustin, Shawn X. Yin, +10

Science

Diverse crystal size effects in covalent organic frameworks

Tianqiong Ma, Lei Wei, Lin Liang, +8

Nature Communications

Amorphous Drug-PVP Dispersions: Application of Theoretical, Thermal and Spectroscopic Analytical Techniques to the Study of a Molecule With Intermolecular Bonds in Both the Crystalline and Pure Amorphous State

Jonathan Brown, Andrew B. Dennis, M. Fakes, +8

Journal of Pharmaceutical Sciences

Materials ScienceEngineeringPolymer SolutionPolymer SciencePhysical Chemistry +7

Bioavailability enhancement of a COX-2 inhibitor, BMS-347070, from a nanocrystalline dispersion prepared by spray-drying

Shawn X. Yin, Miriam Franchini, Jinling Chen, +5

Journal of Pharmaceutical Sciences

NanomedicineMedicinal ChemistryPharmaceutical ScienceCox-2 InhibitorMedicine +6

Understanding the Origins of Conformational Disorder in the Crystalline Polymorphs of Irbesartan

Sean P. Delaney, Duohai Pan, Michael A. Galella, +2

Crystal Growth & Design

Crystal StructureEngineeringMolecular BiologyComputational ChemistryChemistry +14

Evaluating the Roles of Conformational Strain and Cohesive Binding in Crystalline Polymorphs of Aripiprazole

Sean P. Delaney, Duohai Pan, Shawn X. Yin, +2

Crystal Growth & Design

Relative StabilitiesEngineeringComputational ChemistryChemistryMolecular Dynamics +15

Molecular Basis of Crystal Morphology-Dependent Adhesion Behavior of Mefenamic Acid During Tableting

Vrushali Waknis, Elza Chu, Roxana F. Schlam, +4

Pharmaceutical Research

Adhesive MaterialMefenamic AcidPharmaceutical TechnologyMolecular BasisPharmacology +1

Low level drug product API form analysis – Avalide tablet NIR quantitative method development and robustness challenges

Duohai Pan, George Crull, Shawn X. Yin, +1

Journal of Pharmaceutical and Biomedical Analysis

Pharmaceutical ScienceMedicineBioanalysisQuantitative PharmacologyPharmaceutical Technology +6

Low-Temperature Phase Transition in Crystalline Aripiprazole Leads to an Eighth Polymorph

Sean P. Delaney, Tiffany M. Smith, Duohai Pan, +2

Crystal Growth & Design

Crystal StructureEngineeringChemistryMedicinal ChemistryCrystalline Aripiprazole Leads +14

Characterization of Phase Separation Propensity for Amorphous Spray Dried Dispersions

Daniel P. McNamara, Shawn X. Yin, Duohai Pan, +3

Molecular Pharmaceutics

Materials SciencePharmaceutical ScienceBiomanufacturingEngineeringExcipients +12