[[(Arylpiperazinyl)alkyl]thio]thieno[2,3-<i>d</i>]pyrimidinone Derivatives as High-Affinity, Selective 5-HT_1A Receptor Ligands

Maria Modica, Maria Santagati, Filippo Russo, +5

Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryFunctional SelectivityMedicineNatural Sciences +11

Synthesis of new thienopyrimidobenzothiazoles and thienopyrimidobenzoxazoles with analgesic and antiinflammatory properties

Filippo Russo, Giuseppe Romeo, NA Santagati, +3

European Journal of Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)DerivativesMedicineAntiinflammatory Properties +7

Design, synthesis and binding properties of novel and selective 5-HT3 and 5-HT4 receptor ligands

Maria Modica, Maria Santagati, Salvatore Guccione, +4

European Journal of Medicinal Chemistry

Functional SelectivityMedicineNon-peptide Ligand5-Ht4 Receptor LigandsBiomolecular Engineering +3

Synthesis and binding properties of novel selective 5-HT3 receptor ligands

Maria Modica, Giuseppe Romeo, Luisa Materia, +6

Bioorganic & Medicinal Chemistry

Functional SelectivityNatural SciencesMedicineReceptor (Biochemistry)Molecular Biology +4

Pyrazolothiazolopyrimidine derivatives as a novel class of anti-inflammatory or antinociceptive agents: synthesis, structural characterization and pharmacological evaluation

Filippo Russo, Salvatore Guccione, Giuseppe Romeo, +5

European Journal of Medicinal Chemistry

Medicinal ChemistryStructural CharacterizationPharmaceutical ScienceMedicinePyrazolothiazolopyrimidine Derivatives +7

High affinity and selectivity of [[(arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives for the 5-HT1A receptor.Synthesis and structure–affinity relationships

Maria Modica, Maria Santagati, Filippo Russo, +3

European Journal of Medicinal Chemistry

Molecular PharmacologyDrug TargetStructure–affinity RelationshipsBiochemistryFunctional Selectivity +9

New Pyrimido[5,4-<i>b</i>]indoles as Ligands for α₁-Adrenoceptor Subtypes

Giuseppe Romeo, Luisa Materia, Fabrizio Manetti, +6

Journal of Medicinal Chemistry

Structural AnaloguesCombinatorial ChemistryMedicinal ChemistryDerivative (Chemistry)Biochemistry +9

Synthesis and pharmacological properties of pyrazolotriazolopyrimidine derivatives

Filippo Russo, Salvatore Guccione, Giuseppe Romeo, +5

European Journal of Medicinal Chemistry

Molecular PharmacologyBiochemistryMedicinePyrazolotriazolopyrimidine DerivativesPharmacological Agent +5

Synthesis of 1,3,4‐thiadiazolo[3,2‐α]pyrimidin‐5‐one and isomeric 7‐one derivatives

Filippo Russo, Andrea Santagati, Maria Santagati

Journal of Heterocyclic Chemistry

Molecular PharmacologyDerivative (Chemistry)DerivativesIsomeric 7‐OneBiochemistry +9

[1,2,4]Triazole derivatives as 5-HT1A serotonin receptor ligands

Maria Sarvà, Giuseppe Romeo, Francesco Guerrera, +6

Bioorganic & Medicinal Chemistry

Functional SelectivityMedicineNeuropharmacologyPharmacotherapyPharmacology +1