Defective removal of ribonucleotides from DNA promotes systemic autoimmunity

Claudia Günther, Barbara Kind, Martin A.M. Reijns, +42

Journal of Clinical Investigation

Rnase H2 DeficiencyGenome InstabilityAutoimmune DiseaseRnase H2Systemic Lupus Erythematosus Treatment +13

Blood-derived iron mediates free radical production and neuronal death in the hippocampal CA1 area following transient forebrain ischemia in rat

Ui Jin Park, Young Ae Lee, Sun Mi Won, +5

Acta Neuropathologica

NeurophysiologyPhysiologyNeuronal DeathSocial SciencesBrain Injury +9

Mechanisms of Oxidation of Guanine in DNA by Carbonate Radical Anion, a Decomposition Product of Nitrosoperoxycarbonate

Young Ae Lee, Byeong Hwa Yun, Seog K. Kim, +4

Chemistry - A European Journal

Carbon DioxideChemical KineticsBioorganic ChemistryMolecular BiologyOrganic Chemistry +17

Oxidation of Guanine in G, GG, and GGG Sequence Contexts by Aromatic Pyrenyl Radical Cations and Carbonate Radical Anions:  Relationship between Kinetics and Distribution of Alkali-Labile Lesions

Young Ae Lee, Alexander Durandin, Peter C. Dedon, +2

The Journal of Physical Chemistry B

Concurrent blockade of free radical and microsomal prostaglandin E synthase‐1‐mediated PGE₂ production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis

Jin Hee Shin, Young Ae Lee, Jae Keun Lee, +7

Journal of Neurochemistry

Photosensitized Oxidative DNA Damage:  From Hole Injection to Chemical Product Formation and Strand Cleavage

Byeong Hwa Yun, Young Ae Lee, Seog K. Kim, +5

Journal of the American Chemical Society

Oxidation of Guanine by Carbonate Radicals Derived from Photolysis of Carbonatotetramminecobalt(III) Complexes and the pH Dependence of Intrastrand DNA Cross‐Links Mediated by Guanine Radical Reactions

Conor Crean, Young Ae Lee, Byeong Hwa Yun, +2

ChemBioChem

Carbon DioxideMolecular BiologyOrganic ChemistryChemistryChemical Biology +17

Oxidative DNA cleavage by Cu(II) complexes: Effect of periphery substituent groups

Wei Wang, Young Ae Lee, Gyeongwon Kim, +6

Journal of Inorganic Biochemistry

Inorganic ChemistryBiochemistryNatural SciencesMetalloproteinBioactive Metal +8

Prevention effects of ND-07, a novel drug candidate with a potent antioxidative action and anti-inflammatory action, in animal models of severe acute pancreatitis

Jin Hwan Lee, Chun San An, Bok Sun Yun, +6

European Journal of Pharmacology

InflammationSevere Acute PancreatitisNovel Drug CandidateAnti-inflammatory ActionAnti-inflammatory +6

AAD-2004 Attenuates Progressive Neuronal Loss in the Brain of Tg-betaCTF99/B6 Mouse Model of Alzheimer Disease

In‐Sun Baek, Taekyung Kim, Ji‐Seon Seo, +5

Experimental Neurobiology