Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells

Lijun Liang, Kaiyuan Hui, Chenxi Hu, +12

Journal of Experimental & Clinical Cancer Research

ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells

Yali Ci, Kejian Shi, Jongkeol An, +5

Cell Death and Disease

The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo

Jongkeol An, Kejian Shi, Wentao Wei, +8

Cell Death and Disease

The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells

Pa Wu, Kejian Shi, Jongkeol An, +5

Cell Death and Disease

Chemoprevention StrategyApoptosisImmunologyCellular IapCell Death +15

Exosomal miR-136-5p Derived from Anlotinib-Resistant NSCLC Cells Confers Anlotinib Resistance in Non-Small Cell Lung Cancer Through Targeting PPP2R2A

Guoqing Gu, Chenxi Hu, Kaiyuan Hui, +4

International Journal of Nanomedicine

Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells

Junzhang Zhao, Rui Zhou, Kaiyuan Hui, +7

Oncotarget

Safety and efficacy of PD-1 blockade-activated multiple antigen-specific cellular therapy alone or in combination with apatinib in patients with advanced solid tumors: a pooled analysis of two prospective trials

Lijun Liang, Yixuan Wen, Rong Hu, +9

Cancer Immunology Immunotherapy

Tumor ImmunologyCancer ImmunosurveillanceMedicineImmunologyAdvanced Solid Tumors +7

Selenite-induced autophagy antagonizes apoptosis in colorectal cancer cells in vitro and in vivo

Yang Yang, Hui Luo, Kaiyuan Hui, +5

Oncology Reports

MitophagyChemoprevention StrategySelenite‑treated Colorectal CancerApoptosisCell Death +17

Role of the NRP-1-mediated VEGFR2-independent pathway on radiation sensitivity of non-small cell lung cancer cells

Chenxi Hu, Panrong Zhu, Youyou Xia, +3

Journal of Cancer Research and Clinical Oncology

Radiation TherapyMedicineCancer BiologyRadiation SensitivityRadiation Oncology +4

Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells

Kejian Shi, Jongkeol An, Lei Shan, +8

Cell Death and Disease

MitophagyApoptosisImmunologyCell DeathIkk Alpha +22