Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis

Junpei Wang, Weili Yang, Zhenzhen Chen, +7

Diabetes

Lncrna SuppressorRecruits Hnrnpa1EngineeringFatty Liver DiseaseInsulin Signaling +21

NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway

Weili Yang, Junpei Wang, Zhenzhen Chen, +10

Diabetes

Fam3a ExpressionFatty Liver DiseaseInsulin SignalingOxidative StressObesity +16

Metformin Alters Gut Microbiota of Healthy Mice: Implication for Its Potential Role in Gut Microbiota Homeostasis

Wei Ma, Ji Chen, Yuhong Meng, +3

Frontiers in Microbiology

FAM3C‐YY1 axis is essential for TGFβ‐promoted proliferation and migration of human breast cancer MDA‐MB‐231 cells via the activation of HSF1

Weili Yang, Biaoqi Feng, Yuhong Meng, +6

Journal of Cellular and Molecular Medicine

VSMC-Specific Deletion of FAM3A Attenuated Ang II-Promoted Hypertension and Cardiovascular Hypertrophy

Rui Xiang, Ji Chen, Shuangyue Li, +8

Circulation Research

FAM3A mediates PPARγ's protection in liver ischemia-reperfusion injury by activating Akt survival pathway and repressing inflammation and oxidative stress

Zhenzhen Chen, Junpei Wang, Weili Yang, +5

Oncotarget

Lipid PeroxidationImmunologyCell DeathNovel Mitochondrial ProteinRedox Biology +18

Defining Essentiality Score of Protein-Coding Genes and Long Noncoding RNAs

Pan Zeng, Ji Chen, Yuhong Meng, +3

Frontiers in Genetics

FAM3A maintains metabolic homeostasis by interacting with F1-ATP synthase to regulate the activity and assembly of ATP synthase

Han Yan, Yuhong Meng, Xin Li, +8

Metabolism

Systems BiologySignal TransductionEnergy MetabolismBiochemistryPhysiology +10

Repurposing Doxepin to Ameliorate Steatosis and Hyperglycemia by Activating FAM3A Signaling Pathway

Zhenzhen Chen, Xiangyang Liu, Yanjin Luo, +6

Diabetes

MeSAUR1, Encoded by a Small Auxin-Up RNA Gene, Acts as a Transcription Regulator to Positively Regulate ADP-Glucose Pyrophosphorylase Small Subunit1a Gene in Cassava

Ping-An Ma, Xin Chen, Chen Liu, +5

Frontiers in Plant Science