Hanjie Yi

A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma

Hanjie Yi, Xianglei Yan, Qiuyun Luo et al. · Journal of Experimental & Clinical Cancer Research · 2018 · 68 citations · Full text

A Novel BCL-2 Inhibitor APG-2575 Exerts Synthetic Lethality With BTK or MDM2-p53 Inhibitor in Diffuse Large B-Cell Lymphoma

Qiuyun Luo, Wentao Pan, Suna Zhou et al. · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · 2020 · 51 citations · Full text

Hematological Malignancy, Tumor Biology, Lymphoid Neoplasia +15

Bcl‐2/Bcl‐xl inhibitor APG‐1252‐M1 is a promising therapeutic strategy for gastric carcinoma

Hanjie Yi, Miao‐Zhen Qiu, Luping Yuan et al. · Cancer Medicine · 2020 · 49 citations · Full text

Gastric Cancer Cells, Apoptosis, Gastroenterology +18

A novel SMAC mimetic APG-1387 exhibits dual antitumor effect on HBV-positive hepatocellular carcinoma with high expression of cIAP2 by inducing apoptosis and enhancing innate anti-tumor immunity

Wentao Pan, Qiuyun Luo, Xianglei Yan et al. · Biochemical Pharmacology · 2018 · 44 citations

Apoptosis, Immunology, Tumor Immunity +12

Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells

Haibo Chen, Dingyuan Luo, Lin Zhang et al. · Oncotarget · 2017 · 28 citations · Full text

Tumor Biology, P53 Function, Oncology +12