Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer

Allen W. Zhang, Andrew McPherson, Katy Milne, +42

Cell

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Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing

Emma Laks, Andrew McPherson, Hans Zahn, +43

Cell

Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes

Yi Kan Wang, Ali Bashashati, Michael S. Anglesio, +33

Nature Genetics

Genome InstabilityGenomic ConsequencesSomatic VariantGeneticsOvarian Cancer Histotypes +6

Ovarian cancer mutational processes drive site-specific immune evasion

Ignacio Vázquez-Garćıa, Florian Uhlitz, Nicholas Ceglia, +58

Nature

Synchronous Endometrial and Ovarian Carcinomas: Evidence of Clonality

Michael S. Anglesio, Yi Kan Wang, Madlen Maassen, +18

JNCI Journal of the National Cancer Institute

Many WomenSimultaneous CancerTumoral PathologyTumor HeterogeneityMedicine +11

Clonal fitness inferred from time-series modelling of single-cell cancer genomes

Sohrab Salehi, Farhia Kabeer, Nicholas Ceglia, +103

Nature

Clonal FitnessFunctional GenomicsTumor HeterogeneityMedicineGenetics +10

Single-cell genomic variation induced by mutational processes in cancer

Tyler Funnell, Ciara H. O’Flanagan, Marc Williams, +115

Nature

Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models

Tyler Funnell, Allen W. Zhang, Diljot Grewal, +4

PLoS Computational Biology

Structural VariationMachine LearningEngineeringGeneticsMutation Signatures +20

Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes

Minsoo Kim, Alexander N. Gorelick, Ignacio Vázquez-Garćıa, +18

Nature Genetics

GeneticsGenomicsTumor BiologyMitochondrial BiogenesisTumor Heterogeneity +17

Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations

Marc Williams, Michael Oliphant, Vinci Au, +22

Nature Genetics