Mitochondrial Reactive Oxygen Species Mediate Lysophosphatidylcholine-Induced Endothelial Cell Activation

Xinyuan Li, Pu Fang, Yafeng Li, +16

Arteriosclerosis Thrombosis and Vascular Biology

Low-Intensity Ultrasound-Induced Anti-inflammatory Effects Are Mediated by Several New Mechanisms Including Gene Induction, Immunosuppressor Cell Promotion, and Enhancement of Exosome Biogenesis and Docking

Qian Yang, Gayani Nanayakkara, Charles Drummer, +14

Frontiers in Physiology

Central activation of PPAR-gamma ameliorates diabetes induced cognitive dysfunction and improves BDNF expression

Thiruchelvam Kariharan, Gayani Nanayakkara, Kodeeswaran Parameshwaran, +7

Neurobiology of Aging

Ppar-gamma AmelioratesBdnf ExpressionMedicineDiabetesNeurochemical Biomarkers +6

A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors

Luqiao Wang, Gayani Nanayakkara, Qian Yang, +20

Journal of Hematology & Oncology

Interleukin-17A Promotes Aortic Endothelial Cell Activation via Transcriptionally and Post-translationally Activating p38 Mitogen-activated Protein Kinase (MAPK) Pathway

Jietang Mai, Gayani Nanayakkara, Jahaira Lopez‐Pastrana, +14

Journal of Biological Chemistry

InflammationCytokineAtherosclerosisImmunologyEndothelial Dysfunction +4

Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study

Luqiao Wang, Hangfei Fu, Gayani Nanayakkara, +15

Journal of Hematology & Oncology

Interleukin-6 mediates exercise preconditioning against myocardial ischemia reperfusion injury

Graham R. McGinnis, Christopher G. Ballmann, Bridget Peters, +4

American Journal of Physiology-Heart and Circulatory Physiology

Heart FailureIl-6 ReceptorCardiovascular FunctionInflammationKinesiology +15

Lysophospholipids and Their Receptors Serve as Conditional DAMPs and DAMP Receptors in Tissue Oxidative and Inflammatory Injury

Ying Shao, Gayani Nanayakkara, Jiali Cheng, +5

Antioxidants and Redox Signaling

GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg

Keman Xu, William Y. Yang, Gayani Nanayakkara, +6

Frontiers in Immunology

Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells – Novel qualification markers for chronic disease risk factors and conditional DAMPs

Yifan Lu, Yu Sun, Charles Drummer, +13

Redox Biology

Vascular DiseaseImmunologyImmune DysregulationInflammationSignaling Pathway +19