Synthesis and antitumor properties of 2,5-bis(3′-indolyl)thiophenes: Analogues of marine alkaloid nortopsentin

Patrizia Diana, Anna Carbone, Paola Barraja, +6

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMarine Alkaloid NortopsentinAntitumor PropertiesNatural SciencesOrganic Chemistry +4

3,5-Bis(3′-indolyl)pyrazoles, analogues of marine alkaloid nortopsentin: Synthesis and antitumor properties

Patrizia Diana, Anna Carbone, Paola Barraja, +4

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMarine Alkaloid NortopsentinNatural SciencesMedicineOrganic Chemistry +7

Markovian chemicals "in silico" design (MARCH-INSIDE), a promising approach for computer-aided molecular design I: discovery of anticancer compounds

Humberto González‐Díaz, Ornella Gia, Eugenio Uriarte, +12

Journal of Molecular Modeling

Combinatorial ChemistryEngineeringComputer-aided Molecular DesignRational Drug DesignMarkovian Chemicals +9

Synthesis, in vitro antiproliferative activity and DNA-interaction of benzimidazoquinazoline derivatives as potential anti-tumor agents

Lisa Dalla Via, Ornella Gia, Sebastiano Marciani Magno, +5

Il Farmaco

Medicinal ChemistryDerivativesMedicineBenzimidazoquinazoline DerivativesPotential Anti-tumor Agents +6

New Tetracyclic Analogues of Photochemotherapeutic Drugs 5-MOP and 8-MOP:  Synthesis, DNA Interaction, and Antiproliferative Activity

Lisa Dalla Via, Ornella Gia, Sebastiano Marciani Magno, +3

Journal of Medicinal Chemistry

Reference DrugSynthetic PhotochemistryClick ChemistryDermatologyMedicinal Chemistry +17

Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins

Michael S. Christodoulou, Alessandro Sacchetti, Valentina Ronchetti, +18

Bioorganic & Medicinal Chemistry

Medicinal ChemistryPharmaceutical ScienceBiochemistryMedicineNatural Sciences +6

4‘-Methyl Derivatives of 5-MOP and 5-MOA:  Synthesis, Photoreactivity, and Photobiological Activity

Ornella Gia, Antonella Anselmo, Maria Teresa Conconi, +3

Journal of Medicinal Chemistry

Bioorganic ChemistryEngineeringMolecular BiologySynthetic PhotochemistryOrganic Chemistry +19

Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties

Lisa Dalla Via, Sebastiano Marciani Magno, Ornella Gia, +11

Journal of Medicinal Chemistry

Design, synthesis and photobiological properties of 3,4-cyclopentenepsoralens

Ornella Gia, Sebastiano Marciani Magno, Humberto González‐Díaz, +4

Bioorganic & Medicinal Chemistry

HeterocyclicPhotochemistryPhotobiological PropertiesSynthetic PhotochemistryOrganic Chemistry +1

A new benzoangelicin with strong photobiological activity

Lourdes Santana, Eugenio Uriarte, Lisa Dalla Via, +1

Bioorganic & Medicinal Chemistry Letters

BiochemistryPhotochemistryPhotobiologyPhototoxicityNew Benzoangelicin