Ján Sedlák

Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells

Jana Jakubı́ková, Ján Sedlák, Richard Mithen et al. · Biochemical Pharmacology · 2005 · 173 citations

Caco-2 Cells, Signal Transduction, Signaling Pathway +12

Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications

Jana Jakubı́ková, Sophia Adamia, Maria Kost‐Alimova et al. · Blood · 2011 · 153 citations · Full text

Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines.

Jana Jakubı́ková, Yongping Bao, Ján Sedlák · PubMed · 2005 · 112 citations

Multidrug-resistant Hl60/adr, Chemoprevention Strategy, Apoptosis +24

Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia

Robert Ihnatko, Miroslav Kubeš, Martina Takáčová et al. · International Journal of Oncology · 2006 · 93 citations · Full text

Human Glioblastoma Cells, Extracellular Acidosis, Metabolic Remodeling +23

LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance

Miroslav Barančı́k, V. Boháčová, Ján Sedlák et al. · European Journal of Pharmaceutical Sciences · 2006 · 77 citations

Specific Inhibitor, Signal Transduction, Signaling Pathway +10