Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells

Jana Jakubı́ková, Ján Sedlák, Richard Mithen, +1

Biochemical Pharmacology

Caco-2 CellsSignal TransductionSignaling PathwayBiochemistryG2/m Arrest +10

Lenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implications

Jana Jakubı́ková, Sophia Adamia, Maria Kost‐Alimova, +14

Blood

Isothiocyanates induce cell cycle arrest, apoptosis and mitochondrial potential depolarization in HL-60 and multidrug-resistant cell lines.

Jana Jakubı́ková, Yongping Bao, Ján Sedlák

PubMed

Multidrug-resistant Hl60/adrChemoprevention StrategyApoptosisCell DeathCellular Pharmacology +22

Extracellular acidosis elevates carbonic anhydrase IX in human glioblastoma cells via transcriptional modulation that does not depend on hypoxia

Robert Ihnatko, Miroslav Kubeš, Martina Takáčová, +5

International Journal of Oncology

Human Glioblastoma CellsExtracellular AcidosisMetabolic RemodelingGliomaCellular Physiology +21

LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance

Miroslav Barančı́k, V. Boháčová, Ján Sedlák, +2

European Journal of Pharmaceutical Sciences

Specific InhibitorSignal TransductionSignaling PathwayMedicinePi3k/akt Kinase Pathway +8

MGN-3 arabinoxylan rice bran modulates innate immunity in multiple myeloma patients

Dana Cholujová, Jana Jakubı́ková, Branislav Czako, +5

Cancer Immunology Immunotherapy

Hematological MalignancyAllergyAutoimmune DiseaseImmunologyAutoimmunity +4

P-glycoprotein depresses cisplatin sensitivity in L1210 cells by inhibiting cisplatin-induced caspase-3 activation

Lenka Gibalová, Mário Šereš, Andrej Rusnák, +7

Toxicology in Vitro

Cancer ResearchCisplatin-induced Caspase-3 ActivationSignal TransductionCell RegulationImmunology +6

Arsenic sulfide nanoparticles prepared by milling: properties, free-volume characterization, and anti-cancer effects

Zdenka Lukáčová Bujňáková, Peter Baláž, Petre Makreski, +9

Journal of Materials Science

Materials ScienceNanomedicineChemical EngineeringNanoparticlesEngineering +11

Bacterial Ghosts as Novel Efficient Targeting Vehicles for DNA Delivery to the Human Monocyte-Derived Dendritic Cells

Pavol Kudela, Susanne Paukner, Ulrike Beate Mayr, +5

Journal of Immunotherapy

EngineeringMicrobial PathogensAdaptive Immune SystemImmunologyAntigen Processing +20

Immunophenotypic profile of nucleated erythroid progenitors during maturation in regenerating bone marrow

M. FAJTOVA, A. KOVARIKOVA, Peter Švec, +2

Leukemia & lymphoma/Leukemia and lymphoma

ImmunologyBlood CellImmunophenotypingBone Marrow FailureLaboratory Hematology +14