Germline BAP1 mutations predispose to malignant mesothelioma

Joseph R. Testa, Mitchell Cheung, Jianming Pei, +16

Nature Genetics

MedicineGermline Bap1 MutationsPathologyCancer Genetics

BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation

Angela Bononi, Carlotta Giorgi, Simone Patergnani, +22

Nature

Signal TransductionMitochondrial FunctionMitochondrial DynamicCell SignalingNatural Sciences +6

A global metagenomic map of urban microbiomes and antimicrobial resistance

David Danko, Daniela Bezdan, Evan E. Afshin, +669

Cell

High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma

Masaki Nasu, Mitsuru Emi, Sandra Pastorino, +14

Journal of Thoracic Oncology

Tumoral PathologySomatic Bap1 AlterationsPathologyRadiation OncologyMalignant Disease

Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation

Haining Yang, Zeyana Rivera, Sandro Jube, +9

Proceedings of the National Academy of Sciences

Inflammatory Lung DiseaseImmunotoxicologyLung InflammationApoptosisImmunology +22

High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma

Yoshie Yoshikawa, Mitsuru Emi, Tomoko Hashimoto-Tamaoki, +17

Proceedings of the National Academy of Sciences

Biallelic InactivationTumoral PathologyOncologySomatic VariantMalignant Disease +13

A Subset of Mesotheliomas With Improved Survival Occurring in Carriers of<i>BAP1</i>and Other Germline Mutations

Sandra Pastorino, Yoshie Yoshikawa, Harvey I. Pass, +18

Journal of Clinical Oncology

Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s

Michele Carbone, Erin Flores, Mitsuru Emi, +19

PLoS Genetics

EngineeringGeneticsPathologyMolecular GeneticsDisease Gene Identification +14

The SEQC2 epigenomics quality control (EpiQC) study

Jonathan Foox, Jessica Nordlund, Claudia Lalancette, +54

Genome biology

Heterozygous germline <i>BLM</i> mutations increase susceptibility to asbestos and mesothelioma

Angela Bononi, Keisuke Goto, Güntülü Ak, +24

Proceedings of the National Academy of Sciences