Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

Helen S. Bateup, Emanuela Santini, Weixing Shen, +6

Proceedings of the National Academy of Sciences

Inhibition of mTOR Signaling in Parkinson’s Disease Prevents <scp>l</scp> -DOPA–Induced Dyskinesia

Emanuela Santini, Myriam Heiman, Paul Greengard, +2

Science Signaling

<scp>l</scp>‐DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice

Emanuela Santini, Cristina Alcacer, Silvia Cacciatore, +6

Journal of Neurochemistry

Histone H3Dopamine-depleted StriatumSynaptic TransmissionNeurotransmissionSynaptic Signaling +16

Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia

Francesco Napolitano, Massimo Pasqualetti, Alessandro Usiello, +14

Neurobiology of Disease

Molecular PharmacologyFunctional SelectivityMedicinePhysiologyNeurotransmitter +5

Gα_olfMutation Allows Parsing the Role of cAMP-Dependent and Extracellular Signal-Regulated Kinase-Dependent Signaling in l-3,4-Dihydroxyphenylalanine-Induced Dyskinesia

Cristina Alcacer, Emanuela Santini, Emmanuel Valjent, +3

Journal of Neuroscience

Molecular RegulationSynaptic TransmissionNeurotransmitterSynaptic SignalingSocial Sciences +25

Dopamine- and cAMP-regulated Phosphoprotein of 32-kDa (DARPP-32)-dependent Activation of Extracellular Signal-regulated Kinase (ERK) and Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Experimental Parkinsonism

Emanuela Santini, Michael Feyder, Giuseppe Gangarossa, +3

Journal of Biological Chemistry

The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons

Francesco Errico, Emanuela Santini, Sara Migliarini, +12

Molecular and Cellular Neuroscience

NeurotransmitterGtp-binding Protein RhesNeurotransmissionNeuroscienceMolecular Neurobiology +5

Operant behavior to obtain palatable food modifies neuronal plasticity in the brain reward circuit

Thomas Guegan, Laura Cutando, Eduard Ayuso, +7

European Neuropsychopharmacology

Synaptic PlasticityBehavioral SciencesAppetite ControlNeurobiological MechanismBrain Reward Circuit +9

Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation

Charles A. Hoeffer, Emanuela Santini, Tao Ma, +6

Journal of Neurophysiology

Persistent FormsSynaptic SignalingSocial SciencesSignaling PathwayNeurochemistry +16

Delayed, context- and dopamine D1 receptor-dependent activation of ERK in morphine-sensitized mice

Anders Borgkvist, Emmanuel Valjent, Emanuela Santini, +3

Neuropharmacology

Functional SelectivityMedicineNeuropeptide ReceptorNeuropharmacologyNeuroscience +4