Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state

Jürgen den Hollander, Sara Rimpi, Joanne R. Doherty, +14

Blood

Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma

Alexander Hoellein, Mohammad Fallahi, Stephanie Schoeffmann, +10

Blood

A case of paroxysmal nocturnal hemoglobinuria caused by a germline mutation and a somatic mutation in PIGT

Peter Krawitz, Britta Höchsmann, Yoshiko Murakami, +12

Blood

Aurora Kinase Inhibition Overcomes Cetuximab Resistance in Squamous Cell Cancer of the Head and Neck

Alexander Hoellein, Anja Pickhard, Fabienne von Keitz, +9

Oncotarget

Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention

Tracy O’Connor, Xíaolan Zhou, Jan Kosla, +39

Cancer Cell

Neuro-oncologyMedicinePathologyCellular SenescenceBrain-immune Interaction +7

Serious outbreak of human metapneumovirus in patients with hematologic malignancies

Alexander Hoellein, Judith S. Hecker, Dieter Hoffmann, +4

Leukemia & lymphoma/Leukemia and lymphoma

Diagnostic VirologySerious OutbreakHmpv A2 InfectionViral PersistenceViral Diagnostics +12

Cks1 Promotion of S Phase Entry and Proliferation Is Independent of p27 ^Kip1 Suppression

Alexander Hoellein, Steffi Graf, Florian Bassermann, +8

Molecular and Cellular Biology

Skp2 Directs Myc-Mediated Suppression of p27Kip1 yet Has Modest Effects on Myc-Driven Lymphomagenesis

Jennifer B. Old, Susanne Kratzat, Alexander Hoellein, +7

Molecular Cancer Research

ImmunologyPathologyHas Modest EffectsMyc-mediated SuppressionCancer Biology +15

Design, synthesis and biological activity of <i>N</i>⁴-phenylsubstituted-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-amines as dual inhibitors of aurora kinase A and epidermal growth factor receptor kinase

Sonali Kurup, Bradley S. McAllister, Pavlina Liskova, +6

Journal of Enzyme Inhibition and Medicinal Chemistry

Chemical BiologyPharmaceutical ChemistryMolecular PharmacologyMedicinal ChemistryAurka Inhibition +17

Cks1 Is Required for Tumor Cell Proliferation but Not Sufficient to Induce Hematopoietic Malignancies

Susanne Kratzat, Viktoriya D. Nikolova, Cornelius Miething, +10

PLoS ONE

ImmunologyImmunotherapyCancer BiologyTumor BiologyCell Regulation +14