Universal Vaccine Based on Ectodomain of Matrix Protein 2 of Influenza A: Fc Receptors and Alveolar Macrophages Mediate Protection

Karim El Bakkouri, Francis J. Descamps, Marina De Filette, +7

The Journal of Immunology

Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies

Marina De Filette, Wouter Martens, Anouk Smet, +5

Vaccine

VaccinologyVaccinationCross-protectionVaccine DevelopmentVaccine Target +8

Single-Domain Antibodies Targeting Neuraminidase Protect against an H5N1 Influenza Virus Challenge

Francisco Miguel Lopez Cardoso, Lorena Itatí Ibañez, Silvie Van den Hoecke, +9

Journal of Virology

Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

Silvie Van den Hoecke, Katrin Ehrhardt, Annasaheb Kolpe, +14

Journal of Virology

Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies

Michael Schotsaert, Tine Ysenbaert, Anouk Smet, +7

Scientific Reports

Reverse engineering synthetic antiviral amyloids

Emiel Michiels, Kenny Roose, Rodrigo Gallardo, +20

Nature Communications

A GFP Expressing Influenza A Virus to Report In Vivo Tropism and Protection by a Matrix Protein 2 Ectodomain-Specific Monoclonal Antibody

Sarah De Baets, Judith Verhelst, Silvie Van den Hoecke, +7

PLoS ONE

Viral ReplicationImmunologyViral PathogenesisReporter GeneFlu Vaccination +17

Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection

Jochen Pendzialek, Kenny Roose, Anouk Smet, +7

Antiviral Research

VaccinationImmunological MemoryImmunologyAntiviral ResponseInfluenza Vaccine +8

Pre-existing antibodies directed against a tetramerizing domain enhance the immune response against artificially stabilized soluble tetrameric influenza neuraminidase

João Paulo Portela Catani, Emma R. Job, Tine Ysenbaert, +7

npj Vaccines

Anti-neuraminidase and anti-hemagglutinin immune serum can confer inter-lineage cross protection against recent influenza B

João Paulo Portela Catani, Tine Ysenbaert, Anouk Smet, +3

PLoS ONE