Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice

Ivo C. Martins, Inna Kuperstein, Hannah Wilkinson, +9

The EMBO Journal

Molecular NeuroscienceDegenerative PathologyProtein MisfoldingNeuroprotectionNeuroscience +5

ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase

Thomas Tousseyn, Amantha Thathiah, Ellen Jorissen, +10

Journal of Biological Chemistry

Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic–ischemic brain injury

Damjan Osredkar, Marianne Thoresen, Elke Maes, +3

Resuscitation

NeurophysiologyMedicineIntracranial PressureBrain InjuryNeurology +6

Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia

Thomas R. Wood, Damjan Osredkar, Maja Puchades, +6

Scientific Reports

Glu332 in the Nicastrin Ectodomain Is Essential for γ-Secretase Complex Maturation but Not for Its Activity

Lucía Chávez‐Gutiérrez, Alexandra Tolia, Elke Maes, +3

Journal of Biological Chemistry

Protein SecretionMolecular BiologyComplex MaturationCellular PhysiologySecretory Granules +15

Hypothermic Neuronal Rescue from Infection-Sensitised Hypoxic-Ischaemic Brain Injury Is Pathogen Dependent

Mari Falck, Damjan Osredkar, Elke Maes, +4

Developmental Neuroscience

Hypothermia Does Not Reverse Cellular Responses Caused by Lipopolysaccharide in Neonatal Hypoxic-Ischaemic Brain Injury

Damjan Osredkar, Hemmen Sabir, Mari Falck, +5

Developmental Neuroscience

Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic–ischaemic brain injury: a single laboratory meta-analysis

Thomas R. Wood, Julia K. Gundersen, Mari Falck, +6

Scientific Reports

Neither Xenon nor Fentanyl Induces Neuroapoptosis in the Newborn Pig Brain

Hemmen Sabir, Sarah Bishop, Nicki Cohen, +4

Anesthesiology

Xenon Combined with Therapeutic Hypothermia Is Not Neuroprotective after Severe Hypoxia-Ischemia in Neonatal Rats

Hemmen Sabir, Damjan Osredkar, Elke Maes, +2

PLoS ONE