Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle

Masakazu Sato, Kei Kawana, Katsuyuki Adachi, +15

Oncotarget

Cancer-associated fibroblast suppresses killing activity of natural killer cells through downregulation of poliovirus receptor (PVR/CD155), a ligand of activating NK receptor

Tomoko Inoue, Katsuyuki Adachi, Kei Kawana, +15

International Journal of Oncology

Chemoprevention StrategyImmunologyPvr ExpressionCell DeathNk Cells +14

Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes

Haruka Nishida, Yōko Matsumoto, Kei Kawana, +26

Journal of Controlled Release

NanomedicineEngineeringPolymer-drug ConjugateImmunologyVirology +6

Predictive factors for recurrence of ovarian mature cystic teratomas after surgical excision

Miyuki Harada, Yutaka Osuga, Asaha Fujimoto, +4

European Journal of Obstetrics & Gynecology and Reproductive Biology

Gynecological SurgeryPredictive FactorsSurgical PathologyGynecologySurgery +3

Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis

Asaha Fujimoto, Kei Kawana, Ayumi Taguchi, +16

Oncotarget

ApoptosisCell DeathCancer BiologyCancer Stem-like CellsTumor Biology +18

Clinical significance of Gremlin 1 in cervical cancer and its effects on cancer stem cell maintenance

Masakazu Sato, Kei Kawana, Asaha Fujimoto, +13

Oncology Reports

Therapeutic significance of targeting survivin in cervical cancer and possibility of combination therapy with TRAIL

Hiroe Nakamura, Ayumi Taguchi, Kei Kawana, +20

Oncotarget

Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer

Hiroe Nakamura, Kazunori Nagasaka, Kei Kawana, +13

BMC Cancer

Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated Peritonitis

Mitsuyo Yoshida, Ayumi Taguchi, Kei Kawana, +18

PLoS ONE

Gastrointestinal OncologyOncogenic AgentMedicineImmunologyBiological Microenvironments +10

The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway

Juri Ogishima, Ayumi Taguchi, Akira Kawata, +15

BMC Cancer