4-Benzylamino-1-chloro-6-substituted Phthalazines:  Synthesis and Inhibitory Activity toward Phosphodiesterase 5

Nobuhisa Watanabe, Yasuhiro Kabasawa, Yasutaka Takase, +5

Journal of Medicinal Chemistry

Novel Features of Eukaryotic Photosystem II Revealed by Its Crystal Structure Analysis from a Red Alga

Hideo Ago, Hideyuki Adachi, Yasufumi Umena, +12

Journal of Biological Chemistry

BiologyPhotorespirationPhotochemistryPhotosystemsBiochemistry +12

Relaxant Effects of Pyranocoumarin Compounds Isolated from a Chinese Medical Plant, Bai-Hua Qian-Hu, on Isolated Rabbit Tracheas and Pulmonary Arteries.

Wan-Bao JIN, Xinhua Zhang, Yu Sun, +2

Biological and Pharmaceutical Bulletin

Pyranocoumarin Compounds IsolatedLung InflammationPulmonary HypertensionPharmacotherapyChinese Medical Plant +14

Towards structural elucidation of eukaryotic photosystem II: Purification, crystallization and preliminary X-ray diffraction analysis of photosystem II from a red alga

Hideyuki Adachi, Yasufumi Umena, Isao Enami, +3

Biochimica et Biophysica Acta (BBA) - Bioenergetics

X-ray CrystallographyPhotosystem IiBiochemistryPhotosystemsNatural Sciences +10

4-(3-Chloro-4-methoxybenzyl)aminophthalazines:  Synthesis and Inhibitory Activity toward Phosphodiesterase 5

Nobuhisa Watanabe, Hideyuki Adachi, Yasutaka Takase, +9

Journal of Medicinal Chemistry

Combinatorial ChemistryInhibitory ActivityMedicinal ChemistryBiochemistryNatural Sciences +9

E-4010, a selective phosphodiesterase 5 inhibitor, attenuates hypoxic pulmonary hypertension in rats

N. Hanasato, Masahiko Oka, Masashi Muramatsu, +3

American Journal of Physiology-Lung Cellular and Molecular Physiology

Improvement of Mortality by Long-Term E4010 Treatment in Monocrotaline-Induced Pulmonary Hypertensive Rats

Kohtarou Kodama, Hideyuki Adachi

Journal of Pharmacology and Experimental Therapeutics

Characteristics of the Inhibition of Ligand Binding to Serotonin Receptors in Rat Brain Membranes by Verapamil

Hideyuki Adachi, T. Shoji

The Japanese Journal of Pharmacology

NeurotransmitterPharmacotherapyLigand BindingExperimental PharmacologySocial Sciences +17

Effects of ionic and nonionic contrast media on coronary diameter and blood flow in chronically instrumented dogs

Shogo Egashira, Hitonobu Tomoike, H Nishijima, +2

American Heart Journal

Veterinary PhysiologyCardiovascular DiseaseCoronary DiameterPhysiologyVeterinary Science +10

Aromatic structure of Tyrosine‐92 in the extrinsic PsbU protein of red algal Photosystem II is important for its functioning

Akinori Okumura, Masanori Sano, Takehiro Suzuki, +7

FEBS Letters

Crystal StructurePhotorespirationBiochemistryPhotosystemsPhotochemistry +13