Toxic effect of tumor necrosis factor on tumor vasculature in mice.

Naoki Watanabe, Yoshiro Niitsu, Hiroshi Umeno, +5

PubMed

Cell TherapyVasculitisImmunologyPathologyImmunotherapy +21

Intracellular hydroxyl radical production induced by recombinant human tumor necrosis factor and its implication in the killing of tumor cells in vitro.

Naofumi Yamauchi, Hiroshi Kuriyama, Naoki Watanabe, +3

PubMed

Chemoprevention StrategyLipid PeroxidationApoptosisImmunologyCell Death +17

Synergistic cytotoxic and antitumor effects of recombinant human tumor necrosis factor and hyperthermia.

Naoki Watanabe, Yoshiro Niitsu, Hiroshi Umeno, +5

PubMed

Chemoprevention StrategyApoptosisImmunologyCell DeathPharmacotherapy +19

Continuous internalization of tumor necrosis factor receptors in a human myosarcoma cell line.

Naoki Watanabe, Hiroshi Kuriyama, H Sone, +4

Journal of Biological Chemistry

ApoptosisImmunologyImmunoeditingPathologyImmunologic Mechanism +14

Synergistic effects of recombinant human tumor necrosis factor and hyperthermia on in vitro cytotoxicity and artificial metastasis.

Yoshiro Niitsu, Naoki Watanabe, Hiroshi Umeno, +5

PubMed

Human Embryonic LungApoptosisImmunologyCell DeathPathology +17

Induction of Heat Shock Protein 47 Synthesis by TGF-β and IL-1β Via Enhancement of the Heat Shock Element Binding Activity of Heat Shock Transcription Factor 1

Hiroyoshi Sasaki, Tsutomu Sato, Naofumi Yamauchi, +10

The Journal of Immunology

Inflammatory Lung DiseaseImmune RegulationImmunologyPathologyImmunologic Mechanism +18

Serum Tumor Necrosis Factor Activity in Inflammatory Bowel Disease

Masahiro Maeda, Naoki Watanabe, H Neda, +7

Immunopharmacology and Immunotoxicology

InflammationAutoimmune DiseaseImmunologyGastroenterologyPathology +8

Antitumor effect of tumor necrosis factor against various primarily cultured human cancer cells.

Naoki Watanabe, Yoshiro Niitsu, H Neda, +4

PubMed

ApoptosisImmunologyCell DeathPathologyImmunotherapy +15

Suppressive effects of intracellular glutathione on hydroxyl radical production induced by tumor necrosis factor

Naofumi Yamauchi, Naoki Watanabe, Hiroshi Kuriyama, +4

International Journal of Cancer

Treatment of murine collagen-induced arthritis by ex vivo extracellular superoxide dismutase gene transfer

Satoshi Iyama, Tetsuro Okamoto, Tsutomu Sato, +10

Arthritis & Rheumatism