Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

Bahram Namjou, Parul H. Kothari, Jennifer A. Kelly, +35

Genes and Immunity

Autoimmune DiseaseTrex1 GeneLupusGeneticsLupus Nephritis +9

A hairpin ribozyme inhibits expression of diverse strains of human immunodeficiency virus type 1.

Meichen Yu, J O Ojwang, Osamu Yamada, +4

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyMolecular BiologyMultiple Hiv-1 StrainsDiverse Strains +14

Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme.

J O Ojwang, Arnold Hampel, D. J. Looney, +2

Proceedings of the National Academy of Sciences

Hairpin RibozymeViral ReplicationHuman RetrovirusImmunologyAntiviral Response +10

Evaluation of imputation-based association in and around the integrin- -M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE)

Shizhong Han, Xana Kim-Howard, Hitesh Deshmukh, +25

Human Molecular Genetics

T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1

J O Ojwang, Robert W. Buckheit, Yves Pommier, +7

Antimicrobial Agents and Chemotherapy

Hiv-1 IntegrasePotent InhibitorImmunologyMolecular BiologyT30177 Inhibited Replication +20

Synthesis of a duplex oligonucleotide containing a nitrogen mustard interstrand DNA-DNA cross-link.

J O Ojwang, Dorre A. Grueneberg, Edward L. Loechler

PubMed

ChromatinDuplex OligonucleotideNucleic Acid ChemistryDnaDna Nanotechnology +12

The Lupus Family Registry and Repository

Astrid Rasmussen, Sydney T. Sevier, Jennifer A. Kelly, +39

Lara D. Veeken

Genetic TestingGeneticsGenetic EpidemiologyLupus CasesGenomics +20

Identification of new SLE-associated genes with a two-step Bayesian study design

Don Armstrong, Andreas Reiff, Barry L. Myones, +22

Genes and Immunity

Inhibition of human immunodeficiency virus type 1 activity in vitro by oligonucleotides composed entirely of guanosine and thymidine.

J O Ojwang, Ahmed Elbaggari, Hélène B. Marshall, +3

PubMed

ImmunologyMolecular BiologyCell CultureHiv-1 GenomeAntiviral Drug +17

Construction of a human shuttle vector containing a single nitrogen mustard interstrand, DNA-DNA cross-link at a unique plasmid location.

Dorre A. Grueneberg, J O Ojwang, Matt Benasutti, +2

PubMed

Duplex OligonucleotideEngineeringGeneticsDna AnalysisMolecular Biology +18