Richard Wu

Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

Evan A. Stein, Scott Mellis, George D. Yancopoulos et al. · New England Journal of Medicine · 2012 · 659 citations · Full text

Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial

Evan A. Stein, Dan Gipe, Jean Bergeron et al. · The Lancet · 2012 · 575 citations

Metabolic Syndrome, Cardiovascular Disease, Stable Statin Dose +7

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

Diamant Thaçi, Eric L. Simpson, Lisa A. Beck et al. · The Lancet · 2015 · 560 citations

Allergy, Atopic Dermatitis, Allergy Medicine +7

Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults

Eric L. Simpson, Thomas Bieber, Laurent Eckert et al. · Journal of the American Academy of Dermatology · 2016 · 299 citations

Dupilumab therapy provides clinically meaningful improvement in patient-reported outcomes (PROs): A phase IIb, randomized, placebo-controlled, clinical trial in adult patients with moderate to severe atopic dermatitis (AD)

Eric L. Simpson, Abhijit Gadkari, Margitta Worm et al. · Journal of the American Academy of Dermatology · 2016 · 160 citations

Meaningful Improvement, Atopic Dermatitis, Clinical Trials +7