G C Ness

A molecular defect in hepatic cholesterol biosynthesis in sitosterolemia with xanthomatosis.

L. B. Nguyen, Sarah Shefer, G Salen et al. · Journal of Clinical Investigation · 1990 · 107 citations · Full text

Pathology, Hyperlipidemia, Oxidative Stress +18

Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers.

Irwin Singer, D W Kawka, D M Kazazis et al. · Proceedings of the National Academy of Sciences · 1984 · 99 citations · Full text

Lipid Peroxidation, Fatty Liver Disease, Oxidative Stress +21

Differing effects of cholesterol and taurocholate on steady state hepatic HMG-CoA reductase and cholesterol 7 alpha-hydroxylase activities and mRNA levels in the rat.

Sarah Shefer, L B Nguyen, G Salen et al. · Journal of Lipid Research · 1992 · 88 citations · Full text

Transcriptional and posttranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase by thyroid hormones.

W. Scott Simonet, G C Ness · Journal of Biological Chemistry · 1988 · 73 citations · Full text

Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels

G C Ness, R. Kennedy Keller, Laura C. Pendleton · Journal of Biological Chemistry · 1991 · 72 citations · Full text