J. Sigmond - Concepedia

Author

J. Sigmond

Amsterdam UMC Location Vrije Universiteit Amsterdam

Also Known As

J Sigmond, J. Sigmond, Jennifer Sigmond

Publications

487

Citations

H-Index

Concepts

All Affiliations

Amsterdam UMC Location Vrije Universiteit Amsterdam The Netherlands Cancer Institute University Hospital and Clinics University Medical Center

About

J. Sigmond is an author at Amsterdam UMC Location Vrije Universiteit Amsterdam specializing in medicine, natural sciences, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	302
2	Natural Sciences	3	3	99
3	Biochemistry	3	3	99
4	Cell Biology	2	2	161
5	Chemical Biology	1	1	25

J. Sigmond

Publications

427

Citations

H-Index

Page 1

	Year	Citations
Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression J. Sigmond, Harold H.J. Backus, Dorine Wouters, Biochemical Pharmacology Oncogenic AgentMedicineThymidylate Synthase OverexpressionImmunologyAntifolate Pemetrexed	2003	147
Gemcitabine uptake in glioblastoma multiforme: potential as a radiosensitizer J. Sigmond, Richard J. Honeywell, Tjeerd J. Postma, Annals of Oncology Neuro-oncologyRadiation TherapyGliomaMedicineGemcitabine Uptake	2008	89
Synthesis and Biological Activity of a Gemcitabine Phosphoramidate Prodrug Weidong Wu, J. Sigmond, Godefridus J. Peters, Journal of Medicinal Chemistry Cell-based Drug DeliveryMedicinal ChemistryPharmaceutical ScienceBiochemistryDck Deficiency	2007	52
Molecular pathways involved in the synergistic interaction of the PKCβ inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells Christina Tekle, Elisa Giovannetti, J. Sigmond, British Journal of Cancer	2008	45
The synergistic interaction of gemcitabine and cytosine arabinoside with the ribonucleotide reductase inhibitor triapine is schedule dependent J. Sigmond, J. A. E. Kamphuis, Adrianus C. Laan, Biochemical Pharmacology BiochemistryNatural SciencesProtein BiosynthesisMolecular BiologyDna Replication	2007	25
Quantitative real time PCR of deoxycytidine kinase mRNA by Light Cycler PCR in relation to enzyme activity and gemcitabine sensitivity J. Sigmond, Judith R. Kroep, Willem J.P Loves, Cancer Letters BiochemistryLight Cycler PcrGemcitabine SensitivityNatural SciencesBioanalysis	2004	22
Immunocytochemical detection of deoxycytidine kinase in haematological malignancies and solid tumours Isabelle Hubeek, Godefridus J. Peters, A. J. F. Broekhuizen, Journal of Clinical Pathology	2005	17
Time course of enhanced activity of deoxycytidine kinase and thymidine kinase 1 and 2 in cultured human squamous lung carcinoma cells, SW-1573, induced by γ-irradiation J. Haveman, J. Sigmond, Chris van Bree, Oncology Reports	2006	16
Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase J. Sigmond, Andries M. Bergman, Leticia G. León, Anti-Cancer Drugs Deoxycytidine KinaseCancer BiologyOxidative StressDck ActivityGemcitabine Sensitivity	2010	14

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