CRTAP Is Required for Prolyl 3- Hydroxylation and Mutations Cause Recessive Osteogenesis Imperfecta

Roy Morello, Terry Bertin, Yuqing Chen, +17

Cell

SclerostinDevelopmental BiologyBone Morphogenic ProteinGeneticsProlyl 3- Hydroxylation +4

Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes

Shawna M. Pyott, Ulrike Schwarze, Helena E. Christiansen, +14

Human Molecular Genetics

GeneticsOsteogenesisMolecular GeneticsOsteoporosisBone Morphogenic Protein +17

Abnormal Type I Collagen Post-translational Modification and Crosslinking in a Cyclophilin B KO Mouse Model of Recessive Osteogenesis Imperfecta

Wayne A. Cabral, Irina Perdivara, MaryAnn Weis, +12

PLoS Genetics

Targeting the LRP5 Pathway Improves Bone Properties in a Mouse Model of Osteogenesis Imperfecta

Christina M. Jacobsen, Lauren A. Barber, Ugur M. Ayturk, +8

Journal of Bone and Mineral Research

Increased C-telopeptide Cross-linking of Tendon Type I Collagen in Fibromodulin-deficient Mice

Sebastian Kalamajski, Cuiping Liu, Viveka Tillgren, +5

Journal of Biological Chemistry

Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta

Wayne A. Cabral, Masaki Ishikawa, Matthias Garten, +15

PLoS Genetics

A Novel 3-Hydroxyproline (3Hyp)-rich Motif Marks the Triple-helical C Terminus of Tendon Type I Collagen

David R. Eyre, MaryAnn Weis, David M. Hudson, +2

Journal of Biological Chemistry

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation

Melissa E. Heard, Roberta Besio, MaryAnn Weis, +13

PLoS Genetics

SclerostinSkin FragilityOsteogenesisCytoskeletonCellular Physiology +17

Non-Lethal Type VIII Osteogenesis Imperfecta Has Elevated Bone Matrix Mineralization

Nadja Fratzl‐Zelman, Aileen M. Barnes, MaryAnn Weis, +12

The Journal of Clinical Endocrinology & Metabolism

Asporin-deficient mice have tougher skin and altered skin glycosaminoglycan content and structure

Marco Maccarana, René B. Svensson, Anki Knutsson, +6

PLoS ONE

Tissue EngineeringEngineeringCollagen Protein ContentImmunologyCross-linked Collagen +20