Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53

Kaipeng Jing, Kyoungsub Song, Soyeon Shin, +14

Autophagy

Docosahexaenoic AcidMitophagyApoptosisCell DeathPathology +17

The Omega-3 Polyunsaturated Fatty Acid DHA Induces Simultaneous Apoptosis and Autophagy via Mitochondrial ROS-Mediated Akt-mTOR Signaling in Prostate Cancer Cells Expressing Mutant p53

Soyeon Shin, Kaipeng Jing, Soyeon Jeong, +12

BioMed Research International

Docosahexaenoic AcidTumor BiologyMutant P53Cell AutophagyOxysterol +12

Acylshikonin Analogs: Synthesis and Inhibition of DNA Topoisomerase-I

Byung‐Zun Ahn, Kyong-Up Baik, Gi‐Ryang Kweon, +2

Journal of Medicinal Chemistry

Omega-3-Polyunsaturated Fatty Acids Suppress Pancreatic Cancer Cell Growth in vitro and in vivo via Downregulation of Wnt/Beta-Catenin Signaling

Kyoungsub Song, Kaipeng Jing, Jong-Seok Kim, +12

Pancreatology

Tumor BiologyPancreatic CancerChemoprevention StrategyOmega-3 Fatty AcidMedicine +6

Docosahexaenoic Acid Induces Cell Death in Human Non-Small Cell Lung Cancer Cells by Repressing mTOR via AMPK Activation and PI3K/Akt Inhibition

Nayeong Kim, Soyeon Jeong, Kaipeng Jing, +8

BioMed Research International

Distinct Mechanisms of Neurodegeneration Induced by Chronic Complex I Inhibition in Dopaminergic and Non-dopaminergic Cells

Gi‐Ryang Kweon, Jeremy D. Marks, Robert Krencik, +4

Journal of Biological Chemistry

Distinct MechanismsChronic Mitochondrial DysfunctionNeurodegeneration InducedNeurotransmitterCell Death +15

Downregulation of APE1/Ref-1 Is Involved in the Senescence of Mesenchymal Stem Cells

Jun Young Heo, Kaipeng Jing, Kyoungsub Song, +11

Stem Cells

ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo

Soyeon Kim, Kaipeng Jing, Soyeon Shin, +12

Oncology Reports

Rottlerin induces autophagy and apoptotic cell death through a PKC-delta-independent pathway in HT1080 human fibrosarcoma cells: The protective role of autophagy in apoptosis

Kyoungsub Song, Jong-Seok Kim, Eun-Jin Yun, +8

Autophagy

MitophagyApoptosisApoptotic Cell DeathPathologyCell Death +15

Docosahexaenoic acid-induced apoptosis is mediated by activation of mitogen-activated protein kinases in human cancer cells

Soyeon Jeong, Kaipeng Jing, Nayeong Kim, +12

BMC Cancer